A meta-analytic review of verbal fluency deficits in depression

Henry, Julie D. and Crawford, John R. (2005) A meta-analytic review of verbal fluency deficits in depression. Journal of Clinical and Experimental Neuropsychology, 27 1: 78-101. doi:10.1080/138033990513654


Author Henry, Julie D.
Crawford, John R.
Title A meta-analytic review of verbal fluency deficits in depression
Journal name Journal of Clinical and Experimental Neuropsychology   Check publisher's open access policy
ISSN 1380-3395
Publication date 2005-01-01
Year available 2005
Sub-type Article (original research)
DOI 10.1080/138033990513654
Open Access Status Not Open Access
Volume 27
Issue 1
Start page 78
End page 101
Total pages 24
Place of publication Philadelphia, USA
Publisher Taylor & Francis Inc
Language eng
Formatted abstract
A prominent view in the neuropsychological literature is that depression is particularly associated with deficits in executive control processes. A meta-analysis of 42 studies with 2306 participants was therefore conducted to investigate the sensitivity of tests of verbal fluency to the pressure of this disorder, as there is a great deal of evidence that theses measures are valid markers of executive dysfunction. When the methodology adopted by other meta-analytic reviews was employed, semantic fluency deficits were found to be substantially larger than the phonemic fluency deficits. However, when a more rigorous method of meta-analysis was adopted, this indicated that the measure are in fact broadly equivalent in their sensitivity to depression, as has been found for patients with focal frontal lobe lesions. However, in contrast to patients with focal frontal lobe injuries, neither deficit qualified as a differential deficit relative to psychomotor speed. Therefore, for patients with depression, deficits on tests of phonemic and semantic fluency may not reflect executive dysfunction, but a more generalized impairment. Evidence is presented that tests of phonemic and semantic fluency may aid in the differential diagnosis of patients with depression and those in the early stages of dementia of the Alzheimer's type.
Keyword Alzheimer disease
Neuropsychological Tests
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Psychology Publications
 
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Created: Tue, 19 Apr 2011, 00:07:51 EST by Lucy O'Brien on behalf of School of Psychology