Clustering of trauma and associations with single and co-occurring depression and panic attack over twenty years

McCutcheon, Vivia V., Heath, Andrew C., Nelson, Elliot C., Bucholz, Kathleen K., Madden, Pamela A. F. and Martin, Nicholas G. (2010) Clustering of trauma and associations with single and co-occurring depression and panic attack over twenty years. Twin Research And Human Genetics, 13 1: 57-65. doi:10.1375/twin.13.1.57

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Author McCutcheon, Vivia V.
Heath, Andrew C.
Nelson, Elliot C.
Bucholz, Kathleen K.
Madden, Pamela A. F.
Martin, Nicholas G.
Title Clustering of trauma and associations with single and co-occurring depression and panic attack over twenty years
Journal name Twin Research And Human Genetics   Check publisher's open access policy
ISSN 1832-4274
Publication date 2010-02-01
Year available 2010
Sub-type Article (original research)
DOI 10.1375/twin.13.1.57
Open Access Status DOI
Volume 13
Issue 1
Start page 57
End page 65
Total pages 9
Place of publication Bowen Hills, QLD, Australia
Publisher Australian Academic Press
Language eng
Abstract Individuals who experience one type of trauma often experience other types, yet few studies have examined the clustering of trauma. This study examines the clustering of traumatic events and associations of trauma with risk for single and co-occurring major depressive disorder (MDD) and panic attack for 20 years after first trauma. Lifetime histories of MDD, panic attack, and traumatic events were obtained from participants in an Australian twin sample. Latent class analysis was used to derive trauma classes based on each respondent's trauma history. Associations of the resulting classes and of parental alcohol problems and familial effects with risk for a first onset of single and co-occurring MDD and panic attack were examined from the year of first trauma to 20 years later. Traumatic events clustered into three distinct classes characterized by endorsement of little or no trauma, primarily nonassaultive, and primarily assaultive events. Individuals in the assaultive class were characterized by a younger age at first trauma, a greater number of traumatic events, and high rates of parental alcohol problems. Members of the assaultive trauma class had the strongest and most enduring risk for single and co-occurring lifetime MDD and panic attack. Assaultive trauma outweighed associations of familial effects and nonassaultive trauma with risk for 10 years following first trauma. Copyright © Australian Academic Press 2011 All Rights Reserved.
Keyword Trauma
Latent class analysis
Q-Index Code C1
Q-Index Status Confirmed Code
Grant ID AA07728
T32 AA07580
T32 MH19960
F31 MH0710390-1
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Medicine Publications
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Created: Wed, 30 Mar 2011, 23:02:46 EST by Debbie Banks on behalf of School of Medicine