Nutrition in adults with cystic fibrosis

Bell, S.C., Bowerman, A.R., Davies, C.A., Campbell, I.A., Shale, D.J. and Elborn, J.S. (1998) Nutrition in adults with cystic fibrosis. Clinical Nutrition, 17 5: 211-215. doi:10.1016/S0261-5614(98)80061-7

Author Bell, S.C.
Bowerman, A.R.
Davies, C.A.
Campbell, I.A.
Shale, D.J.
Elborn, J.S.
Title Nutrition in adults with cystic fibrosis
Journal name Clinical Nutrition   Check publisher's open access policy
ISSN 0261-5614
Publication date 1998-10-01
Sub-type Article (original research)
DOI 10.1016/S0261-5614(98)80061-7
Open Access Status Not Open Access
Volume 17
Issue 5
Start page 211
End page 215
Total pages 5
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Language eng
Formatted abstract
Improved survival has been associated with better nutritional status in patients with cystic fibrosis (CF). In this study we examined the relationship between nutritional state and other measures of clinical severity in adult patients with CF, attending a regional centre. Eighty-one patients (median age 21 years) were studied. Patients with CF were significantly under weight, compared to healthy individuals but were of similar height. Measurements of lung function, FEV1 and FVC were significantly related to body mass index. Lung function was poorer in patients with chronic pseudomonal infection but body weight and body mass index were not significantly different compared to those without such infection. In 53 patients who were alive 4 years later, FEV1 had declined by -10.5 (2.1)% (P < 0.001) but there was no significant change in body weight 1.5 (6.5) kgs. In 23 patients who died or had lung transplantation the change from 1994 to the date of death or transplantation the FEV1 was reduced by -7.9 (11.2)% (P = 0.004) and body weight -2.8 (4.4) kgs (P < 0.01). In 12 patients who had supplemental enteral feeding, the median increase in body weight was 7 kgs over a period of 12 months. This study confirms that young adult patients with CF are significantly under weight and declining health is associated with significant weight loss. in patients with severe malnutrition significant improvement can be achieved by enteral feeding.
Keyword Cystic fibrosis
Enteral feeding
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
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Created: Mon, 14 Mar 2011, 20:45:25 EST