Recanalization of arterial occlusions with a lensed fiber and a holmium: YAG laser

White, Christopher J., Ramee, Stephen R., Collins, Tyrone J., Mesa, Juan E., Paulsen, Daniel B. and Murgo, Joseph P. (1991) Recanalization of arterial occlusions with a lensed fiber and a holmium: YAG laser. Lasers in Surgery and Medicine, 11 3: 250-256. doi:10.1002/lsm.1900110308

Author White, Christopher J.
Ramee, Stephen R.
Collins, Tyrone J.
Mesa, Juan E.
Paulsen, Daniel B.
Murgo, Joseph P.
Title Recanalization of arterial occlusions with a lensed fiber and a holmium: YAG laser
Journal name Lasers in Surgery and Medicine   Check publisher's open access policy
ISSN 0196-8092
Publication date 1991-01-01
Sub-type Article (original research)
DOI 10.1002/lsm.1900110308
Open Access Status Not Open Access
Volume 11
Issue 3
Start page 250
End page 256
Total pages 7
Place of publication Hoboken, NJ, United States
Publisher John Wiley & Sons
Language eng
Formatted abstract
Laser recanalization of totally occluded swine iliac arteries was performed to assess the safety and efficacy of a lensed fiber laser angioplasty system with a holmium:YAG (2.1 μm) laser. Silica lenses of 1.0 mm, 1.3 mm, and 1.5 mm in diameter attached to the distal end of a 300-μm diameter silica fiber delivered fluences of 79.5 J/cm2, 31.4 J/cm2, and 25.5 J/cm2, respectively. The pulse duration of the laser was 250 μsec and the repetition rate was 4 Hz. The mean length of the total occlusions was 5.3 ± 2.0 cm (range 0.5 cm to 8.0 cm). Successful recanalization was obtained in 16/16 lesions without angiographic vessel perforation. Angiographically significant residual stenoses (>50%)remained in every case following successful laser recanalization. Histologically there was minimal evidence of thermal or acoustic tissue injury; however, in 4 of 16 arteries there was evidence of deep arterial dissection following laser recanalization. We conclude that this lensed fiber coupled with a holmium:YAG laser is a safe and effective method for crossing total occlusions in the relatively straight iliac arteries of this animal model.
Keyword Atherosclerotic swine model
Laser angioplasty
Silica lenses
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 14 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 9 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Mon, 14 Mar 2011, 20:33:02 EST