Novel bio-nanochip based on localized surface plasmon resonance spectroscopy of rhombic nanoparticles

Zhu, Shaoli, Li, Fei, Du, Chunlei and Fu, Yongqi (2008) Novel bio-nanochip based on localized surface plasmon resonance spectroscopy of rhombic nanoparticles. Nanomedicine, 3 5: 669-677. doi:10.2217/17435889.3.5.669

Attached Files (Some files may be inaccessible until you login with your UQ eSpace credentials)
Name Description MIMEType Size Downloads
UQ235045_fulltext.pdf ERA evidence - not publicly available application/pdf 6.88MB 0

Author Zhu, Shaoli
Li, Fei
Du, Chunlei
Fu, Yongqi
Title Novel bio-nanochip based on localized surface plasmon resonance spectroscopy of rhombic nanoparticles
Journal name Nanomedicine   Check publisher's open access policy
ISSN 1743-5889
1748-6963
Publication date 2008-10-01
Sub-type Article (original research)
DOI 10.2217/17435889.3.5.669
Open Access Status File (Author Post-print)
Volume 3
Issue 5
Start page 669
End page 677
Total pages 9
Place of publication London, United Kingdom
Publisher Future Medicine
Language eng
Abstract A new silver (Ag) nanostructure with a rectangular distribution array composed of rhombic nanoparticles is described here. The structure has an apparent advantage of strong hot spots that have a much higher signal intensity than that of the previously reported traditional triangular structures. It generates a great enhancement of a localized surface plasmon resonance (LSPR) effect. Moreover, an antigen with longer arm length is applied to strengthen the binding signals of both the antigen and antibody. We performed experiments for the LSPR-induced extinction spectra in each step of the surface modification of the Ag nanoparticles in atmosphere environment. A spectrophotometer was used to measure the extinction spectrum of our proposed nanochip. The results obtained indicate a better sensitivity for our current nanochip than that of the other reported LSPR-based nanochips. Theoretical computational numerical simulation is also carried out with a discrete dipole approximation algorithm. Our computational results are in agreement with the corresponding experimental spectrum. This type of nanochip may have potential utility in many applications, including medical science, biological fields and biochemical analysis.
Keyword Ag particles
Bio-sensing
DDA
LSPR
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Australian Institute for Bioengineering and Nanotechnology Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 16 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 20 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Sat, 12 Mar 2011, 00:36:26 EST by Dr Shaoli Zhu on behalf of Aust Institute for Bioengineering & Nanotechnology