A survey of the 2006-2009 quartz crystal microbalance biosensor literature

Becker, Bernd and Cooper, Matthew A. (2011) A survey of the 2006-2009 quartz crystal microbalance biosensor literature. Journal of Molecular Recognition, 24 5: 754-787. doi:10.1002/jmr.1117


Author Becker, Bernd
Cooper, Matthew A.
Title A survey of the 2006-2009 quartz crystal microbalance biosensor literature
Journal name Journal of Molecular Recognition   Check publisher's open access policy
ISSN 0952-3499
1099-1352
Publication date 2011-09-01
Year available 2011
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1002/jmr.1117
Open Access Status
Volume 24
Issue 5
Start page 754
End page 787
Total pages 34
Place of publication Bognor Regis, United Kingdom
Publisher John Wiley and Sons
Language eng
Abstract Since the publication of the original review of piezoelectric acoustic sensors in this series there has been a consistent, gradual expansion in the number of published papers using ‘quartz crystal microbalances’ (QCM). Between 2001 and 2009, the number of QCM publications per annum has increased from 49 to 273, with a two-fold increase in papers per annum between 2004 and 2008. Within the field, comparing the time covered by the current to the previous review, there are trends towards increasing use of QCM in the study of protein adsorption to surfaces (93% increase), homeostasis (67% increase), protein–protein interactions (40% increase) and carbohydrates (43% increase). New commercial systems have been released that are driving the uptake of the technology for characterization of binding specificities, affinities, kinetics and conformational changes associated with a molecular recognition event. This paper highlights theoretical and practical aspects of the principles that underpin acoustic analysis, then reviews exemplary papers in key application areas involving small molecular weight ligands, carbohydrates, proteins, nucleic acids, viruses, bacteria, cells and membrane interfaces.
Keyword Quartz crystal microbalance
Label-free
Clinical analysis
Biosensor
Membrane
Self-assembled monolayer
Protein adsorption
Cell adhesion
Q-Index Code C1
Q-Index Status Confirmed Code
Grant ID AF 511105
Institutional Status UQ
Additional Notes Accepted for publication 9 November 2010.

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2012 Collection
ERA 2012 Admin Only
Institute for Molecular Bioscience - Publications
 
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Created: Fri, 11 Mar 2011, 18:21:10 EST by Professor Matthew Cooper on behalf of Institute for Molecular Bioscience