Two-phase microfluidic flows

Zhao, Chun-Xia and Middelberg, Anton P. J. (2011) Two-phase microfluidic flows. Chemical Engineering Science, 66 7: 1394-1411. doi:10.1016/j.ces.2010.08.038


Author Zhao, Chun-Xia
Middelberg, Anton P. J.
Title Two-phase microfluidic flows
Journal name Chemical Engineering Science   Check publisher's open access policy
ISSN 0009-2509
1873-4405
Publication date 2011-04-01
Year available 2010
Sub-type Article (original research)
DOI 10.1016/j.ces.2010.08.038
Open Access Status Not yet assessed
Volume 66
Issue 7
Start page 1394
End page 1411
Total pages 18
Editor A. T. Bell
Place of publication Kidlington, Oxford, U.K.
Publisher Pergamon
Language eng
Subject 1500 Chemical Engineering
1600 Chemistry
2604 Applied Mathematics
2209 Industrial and Manufacturing Engineering
Abstract Two phase systems are ubiquitous in processes and products, and in both cases performance is maximized when precise control over the individual phases, and the ensemble, is possible. Microfluidic technologies afford higher levels of control over two-phase systems than is possible in macroscopic process equipment, opening avenues to controlled reactions as well as products having tightly controlled properties including emulsion size distribution. A review of recent progress in two-phase flows in microfluidic devices is presented. The fundamentals of two-phase flows including some important dimensionless numbers are firstly introduced, followed by a review of two-phase flow regimes in gas-liquid and liquid-liquid systems, focusing on microfluidic methods for controlling droplet formation and coalescence. Applications of two-phase microfluidic flows are briefly reviewed, including new approaches to the formation of well-defined complex emulsion which, like a Matryoshka doll, have structure within structure. The large number of recent publications reviewed in this paper highlights the tremendous interest in the fundamental study and use of controlled microfluidic two-phase flows, driven by the promise of highly controlled processes and new products having controlled complexity.
Formatted abstract
Two phase systems are ubiquitous in processes and products, and in both cases performance is maximized when precise control over the individual phases, and the ensemble, is possible. Microfluidic technologies afford higher levels of control over two-phase systems than is possible in macroscopic process equipment, opening avenues to controlled reactions as well as products having tightly controlled properties including emulsion size distribution. A review of recent progress in two-phase flows in microfluidic devices is presented. The fundamentals of two-phase flows including some important dimensionless numbers are firstly introduced, followed by a review of two-phase flow regimes in gas–liquid and liquid–liquid systems, focusing on microfluidic methods for controlling droplet formation and coalescence. Applications of two-phase microfluidic flows are briefly reviewed, including new approaches to the formation of well-defined complex emulsion which, like a Matryoshka doll, have structure within structure. The large number of recent publications reviewed in this paper highlights the tremendous interest in the fundamental study and use of controlled microfluidic two-phase flows, driven by the promise of highly controlled processes and new products having controlled complexity.
© 2010 Elsevier Ltd. All rights reserved.
Keyword Microfluidics
Two-phase flows
Droplet formation
Coalescence
Emulsions
Flow patterns
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Available online 19 September 2010. Special issue: "Microfluidid Engineering ".

 
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Created: Mon, 07 Mar 2011, 21:17:28 EST by Chunxia Zhao on behalf of Aust Institute for Bioengineering & Nanotechnology