Gross muscle morphology and structure in spastic cerebral palsy: A systematic review

Barrett, Rod S. and Lichtwark, Glen A. (2010) Gross muscle morphology and structure in spastic cerebral palsy: A systematic review. Developmental Medicine and Child Neurology, 52 9: 794-804. doi:10.1111/j.1469-8749.2010.03686.x


Author Barrett, Rod S.
Lichtwark, Glen A.
Title Gross muscle morphology and structure in spastic cerebral palsy: A systematic review
Journal name Developmental Medicine and Child Neurology   Check publisher's open access policy
ISSN 0012-1622
Publication date 2010-09-01
Year available 2010
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1111/j.1469-8749.2010.03686.x
Open Access Status Not yet assessed
Volume 52
Issue 9
Start page 794
End page 804
Total pages 11
Place of publication United Kingdom
Publisher Mac Keith Press
Language eng
Abstract AIM This systematic review and critical evaluation of the literature was conducted to determine how gross muscle morphology and structure are altered in individuals with spastic cerebral palsy (CP).
Formatted abstract
Aim:
This systematic review and critical evaluation of the literature was conducted to determine how gross muscle morphology and structure are altered in individuals with spastic cerebral palsy (CP).

Method:

Electronic databases were searched for articles describing studies of muscle morphological and structural properties in individuals with spastic CP. Data describing muscle fascicle length, belly length, fascicle angle, cross-sectional area, volume, and thickness were extracted and effect sizes were computed for comparisons between individuals with spastic CP and typically developed individuals, between the paretic and non-paretic side in individuals with hemiplegia for all muscles examined, and across the full spectrum of gross motor function in individuals with spastic CP.

Results:
The final yield consisted of 15 articles that met the inclusion criteria. The main finding of the review was the consistent evidence for reduced muscle belly length, muscle volume, cross-sectional area, and muscle thickness in the comparisons between paretic and typically developed muscle and the paretic and non-paretic muscle across a range of muscles.

Interpretation:

Given the importance of muscle morphology and structure for generating muscle force, it is likely that the observed alterations that occur secondary to the neural lesion in individuals with spastic CP contribute to muscle weakness and the attendant loss of motor function in spastic CP. © The Authors. Journal compilation © Mac Keith Press 2010.
Keyword Cerebral Palsy
Humans
Muscle
Skeletal
Organ Size
Paresis
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Non HERDC
Non HERDC
School of Human Movement and Nutrition Sciences Publications
 
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Created: Fri, 04 Mar 2011, 00:10:17 EST by Deborah Noon on behalf of School of Human Movement and Nutrition Sciences