Respirology year-in-review 2008: Basic science

Kolb, Martin R. J. and Yang, Ian (2009) Respirology year-in-review 2008: Basic science. Respirology, 14 3: 318-326. doi:10.1111/j.1440-1843.2009.01491.x

Author Kolb, Martin R. J.
Yang, Ian
Title Respirology year-in-review 2008: Basic science
Journal name Respirology   Check publisher's open access policy
ISSN 1323-7799
Publication date 2009-04-01
Year available 2009
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1111/j.1440-1843.2009.01491.x
Open Access Status
Volume 14
Issue 3
Start page 318
End page 326
Total pages 9
Place of publication Richmond, Vic., Australia
Publisher Wiley-Blackwell Publishing Asia
Language eng
Abstract The basic science and translational studies in Respirology in 2008 have extended our understanding of airway, lung and pleural diseases. The studies have shown the usefulness of animal models of pathogenesis, and the relevance of genetic susceptibility and gene-environmental interaction in the development of airway disease. Biomarkers of airway disease, ALI, pleural disease and interstitial lung disease have also been identified. Models of mucus hypersecretion and response to airway infection have extended our knowledge of exacerbations of airway diseases. Several studies have shown how to modify lung injury and repair in animal models, using antioxidants, immunosuppressive agents or specific ventilator techniques. The challenge now will be to take these important observations further, to discover novel methods of diagnosis, prevention and treatment of acute and chronic lung diseases.
Keyword Airway biology
Chronic obstructive pulmonary disease
Lung fibrosis and interstitial lung disease
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Medicine Publications
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Created: Tue, 01 Mar 2011, 22:16:21 EST