The influence of restricted orientation rearing on map structure in primary visual cortex

Giacomantonio, CE, Ibbotson, MR and Goodhill, GJ (2010) The influence of restricted orientation rearing on map structure in primary visual cortex. NeuroImage, 52 3: 875-883. doi:10.1016/j.neuroimage.2009.12.066

Author Giacomantonio, CE
Ibbotson, MR
Goodhill, GJ
Title The influence of restricted orientation rearing on map structure in primary visual cortex
Journal name NeuroImage   Check publisher's open access policy
ISSN 1053-8119
Publication date 2010-09-01
Year available 2009
Sub-type Article (original research)
DOI 10.1016/j.neuroimage.2009.12.066
Open Access Status Not yet assessed
Volume 52
Issue 3
Start page 875
End page 883
Total pages 9
Place of publication Maryland Heights, MO, United States
Publisher Academic Press
Language eng
Subject 2805 Cognitive Neuroscience
2808 Neurology
2700 Medicine
Abstract Visual experience is critical to the development of the structure of the primary visual cortex and, in turn, normal functional vision. The primary visual cortex contains maps of multiple features of the visual input, and these maps are characterised by specific types of geometric relationships. Manipulations of the visual environment during development in animals such as ferrets, cats and monkeys provide an opportunity to probe the rules governing map formation via their effect on these relationships. Here we use a computational model of map formation based on dimension-reduction principles to predict the effect on map relationships of presenting only a single orientation to one eye and the orthogonal orientation to the other eye. Since orientation preference and ocular dominance are now tightly coupled one might expect orientation and ocular dominance contours to lose their normally orthogonal relationship and instead run parallel to each other. However, surprisingly, the model predicts that orthogonal intersection can sometimes be preserved in this case. The model also predicts that orientation pinwheels can migrate from the centre to the borders of ocular dominance columns, and that the wavelengths of the ocular dominance and orientation maps can become coupled. These predictions provide a way to further test the adequacy of dimension reduction principles for explaining map structure under perturbed as well as normal rearing conditions, and thus allow us to deepen our understanding of the effect of the visual environment on visual cortical development. Copyright © 2009 Elsevier Inc. All rights reserved.
Keyword Orientation map
Ocular dominance
Visual deprivation
Visual plasticity
Q-Index Code C1
Q-Index Status Confirmed Code
Grant ID 525459
Institutional Status UQ
Additional Notes Volume Issue: Computational Models of the Brain.

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2010 Higher Education Research Data Collection
Queensland Brain Institute Publications
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Citation counts: TR Web of Science Citation Count  Cited 6 times in Thomson Reuters Web of Science Article | Citations
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Created: Sun, 13 Feb 2011, 04:44:21 EST by Mary-Anne Marrington on behalf of Queensland Brain Institute