The role of corticosteroids in the management of childhood asthma

Van Asperen, P. P., Mellis, C. M. and Sly, P. D. (1992) The role of corticosteroids in the management of childhood asthma. Medical Journal of Australia, 156 1: 48-52.

Author Van Asperen, P. P.
Mellis, C. M.
Sly, P. D.
Title The role of corticosteroids in the management of childhood asthma
Journal name Medical Journal of Australia   Check publisher's open access policy
ISSN 0025-729X
Publication date 1992-01-01
Year available 1992
Sub-type Article (original research)
Open Access Status Not Open Access
Volume 156
Issue 1
Start page 48
End page 52
Total pages 5
Place of publication Strawberry Hills, NSW, Australia
Publisher Australasian Medical Publishing Company
Language eng
Formatted abstract
Objective: To formulate recommendations for the role of corticosteroid therapy in the management of childhood asthma.

Data sources: The recommendations are based on a review of the available literature and a variety of review articles on the efficacy and safety of corticosteroid therapy supplemented by personal experience in managing children with asthma.

Data synthesis: 1. Preventive therapy. Sodium cromoglycate should be considered first-line treatment. Inhaled corticosteroids are indicated in children who tail to achieve control on this therapy or those with severe disease. An initial dosage of 400-600 μg/day is recommended with subsequent variation in dosage related to clinical response. Large volume spacers can be used to improve aerosol delivery and minimise side effects. Indications for specialist assessment include: use of inhaled corticosteroids in children under 3 years of age; the requirement for high dose therapy ( > 600 μg/day); or the need tor regular oral corticosteroids. 2. Acute severe asthma. Systemic corticosteroid therapy is a valuable adjunct in the treatment of acute severe asthma and can be used safely in the short term. The efficacy of high dose inhaled corticosteroids in the management of acute severe asthma requires further evaluation. The need for systemic corticosteroid therapy signals the need for reassessment of that childs usual maintenance therapy.

Conclusion: These recommendations are presented as a guide to the use of corticosteroid therapy in childhood asthma. In the individual child, the benefits of therapy need to be weighed against the possible risks, with the aim of maintaining good asthma control with the minimum dose of corticosteroid.
Keyword Medicine, General & Internal
General & Internal Medicine
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Faculty of Health and Behavioural Sciences -- Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 12 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 13 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Wed, 17 Nov 2010, 21:56:55 EST