Prevention of allergic respiratory disease in infants: current aspects and future perspectives

Holt, Patrick G. and Sly, Peter D. (2007) Prevention of allergic respiratory disease in infants: current aspects and future perspectives. Current Opinion in Allergy and Clinical Immunology, 7 6: 547-555. doi:10.1097/ACI.0b013e3282f14a17


Author Holt, Patrick G.
Sly, Peter D.
Title Prevention of allergic respiratory disease in infants: current aspects and future perspectives
Journal name Current Opinion in Allergy and Clinical Immunology   Check publisher's open access policy
ISSN 1528-4050
1473-6322
Publication date 2007-12-01
Year available 2007
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1097/ACI.0b013e3282f14a17
Open Access Status Not yet assessed
Volume 7
Issue 6
Start page 547
End page 555
Total pages 9
Place of publication Philadelphia, PA, United States
Publisher Lippincott Williams & Wilkins
Language eng
Abstract PURPOSE OF REVIEW: Primary and secondary prevention of severe atopic disease exemplified by atopic asthma represents an increasingly prominent focus of research in paediatric allergy. We review below the rationale for this approach and recent progress in development and testing of a range of potential preventive strategies. RECENT FINDINGS: The principal areas reviewed relate to potential and currently available treatments targeting enhancement of overall immune functions, allergen-specific immunomodulation and respiratory viral infections, particularly during early childhood. SUMMARY: The scientific rationale for prophylaxis of atopic diseases via early intervention strategies targeting young children is increasingly supported by findings from the experimental and clinical literature and significant progress may be expected in the mid-term future.
Keyword asthma
atopy
early childhood
immunomodulation
viral infection
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: Faculty of Health and Behavioural Sciences -- Publications
 
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Created: Wed, 17 Nov 2010, 21:31:55 EST