Molecular Characterization of the Bidder's Organ in the Cane Toad (Bufo marinus)

Abramyan, John, Wilhelm, Dagmar and Koopman, Peter (2010) Molecular Characterization of the Bidder's Organ in the Cane Toad (Bufo marinus). Journal of Experimental Zoology Part B-Molecular and Developmental Evolution, 314B 6: 503-513. doi:10.1002/jez.b.21357


Author Abramyan, John
Wilhelm, Dagmar
Koopman, Peter
Title Molecular Characterization of the Bidder's Organ in the Cane Toad (Bufo marinus)
Journal name Journal of Experimental Zoology Part B-Molecular and Developmental Evolution   Check publisher's open access policy
ISSN 1552-5007
Publication date 2010-09-01
Year available 2010
Sub-type Article (original research)
DOI 10.1002/jez.b.21357
Open Access Status Not yet assessed
Volume 314B
Issue 6
Start page 503
End page 513
Total pages 11
Place of publication New York, N.Y. U.S.A.
Publisher Wiley-Liss,
Language eng
Abstract In toads, both males and females develop a unique gonadal structure called the Bidder's organ (B0), which resembles ovarian tissue and is attached to the anterior part of the gonad It is not clear whether the B0 is a vestigial organ, or has an endocrine function. In this study, we investigated the expression of the gonadal development genes Dmrt1, Sox9, Sf1, Dui, and p450arom in the developing B0 as compared with the gonads of male and female cane toads. We demonstrate that Sf1, Dax1, and p450arom, key genes involved in vertebrate steroidogenesis, are transcriptionally active in the B0 during developmental milestones associated with sexual development and maturation. Furthermore, the pattern of transcriptional activity in the B0 is completely independent of the corresponding gonads in both sexes, despite its ovary-like morphology. These results suggest that the B0 likely has a steroidogenic role in the development of the cane toad, distinct from that of the gonads. J. Exp. Zool. (Mol. Dev. Evol.) 314B:503-513, 2010. (C) 2010 Wiley-Liss, Inc.
Keyword Receptor Steroidogenic Factor-1
Sex Determination
Nuclear Receptor
Gonadal Differentiation
Pleurodles-waltl
Gene Expression
Bufo marinus
Cloning
Orchiectomy
Animal Structures
Animals
Q-Index Code C1
Q-Index Status Confirmed Code
Grant ID 3PCK38
Institutional Status UQ
Additional Notes Article first published online: 21 MAY 2010

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Agriculture and Food Sciences
Institute for Molecular Bioscience - Publications
 
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Created: Sun, 12 Sep 2010, 10:03:14 EST