Calculation of total body water in infancy

Davies, P.S.W. and Wells, J.C.K. (1994) Calculation of total body water in infancy. European Journal of Clinical Nutrition, 48 7: 490-495.


Author Davies, P.S.W.
Wells, J.C.K.
Title Calculation of total body water in infancy
Journal name European Journal of Clinical Nutrition   Check publisher's open access policy
ISSN 0954-3007
Publication date 1994-07-01
Year available 1994
Sub-type Article (original research)
Open Access Status Not yet assessed
Volume 48
Issue 7
Start page 490
End page 495
Total pages 6
Place of publication London, England
Publisher Nature Publishing
Language eng
Subject 1111 Nutrition and Dietetics
1114 Paediatrics and Reproductive Medicine
Abstract Objective: Total body water can be calculated using stable isotopes by two alternative approaches known as the plateau method and the back extrapolation method. These methods treat the isotopic data in different ways and consequently do not necessarily produce identical values for total body water. Total body water was therefore calculated using both methods using two different tracers, H-2 and O-18.
Formatted abstract
Objective:
Total body water can be calculated using stable isotopes by two alternative approaches known as the plateau method and the back extrapolation method. These methods treat the isotopic data in different ways and consequently do not necessarily produce identical values for total body water. Total body water was therefore calculated using both methods using two different tracers, 2H and 18O.

Design:
A cohort of infants was studied at three ages in the first year of life, and the two methods and two tracers compared at each age.

Results:
The plateau method was found to produce values for total body water greater than those obtained by the back extrapolation method at all three ages using both isotopes (P < 0.01 in all cases).

Conclusions:

This difference is due to the different time points at which total body water is calculated. Back extrapolation values correspond more closely to values of total body water obtained by alternative techniques.
Keyword Body Composition
Deuterium
18-Oxygen
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Wed, 08 Sep 2010, 19:33:59 EST