Wiring the brain: The biology of neuronal guidance

Chedotal, Alain and Richards, Linda J. (2010) Wiring the brain: The biology of neuronal guidance. Cold Spring Harbor Perspectives in Biology, 2 6: a001917-1-a001917-17. doi:10.1101/cshperspect.a001917

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Author Chedotal, Alain
Richards, Linda J.
Title Wiring the brain: The biology of neuronal guidance
Journal name Cold Spring Harbor Perspectives in Biology   Check publisher's open access policy
ISSN 1943-0264
Publication date 2010-06-01
Year available 2010
Sub-type Article (original research)
DOI 10.1101/cshperspect.a001917
Open Access Status DOI
Volume 2
Issue 6
Start page a001917-1
End page a001917-17
Total pages 17
Place of publication Woodbury, NY, United States
Publisher Cold Spring Harbor Laboratory Press
Language eng
Abstract The mammalian brain is the most complex organ in the body. It controls all aspects of our bodily functions and interprets the world around us through our senses. It defines us as human beings through our memories and our ability to plan for the future. Crucial to all these functions is how the brain is wired in order to perform these tasks. The basic map of brain wiring occurs during embryonic and postnatal development through a series of precisely orchestrated developmental events regulated by specific molecular mechanisms. Below we review the most important features of mammalian brain wiring derived from work in both mammals and in nonmammalian species. These mechanisms are highly conserved throughout evolution, simply becoming more complex in the mammalian brain. This fascinating area of biology is uncovering the essence of what makes the mammalian brain able to perform the everyday tasks we take for granted, as well as those which give us the ability for extraordinary achievement. © 2010 Cold Spring Harbor Laboratory Press; all rights reserved
Keyword Lateral olfactory tract
Mouse optic chiasm
Development cerebel cortex
Central nervous system
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Article number a001917, pp. 1-17

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
Queensland Brain Institute Publications
School of Biomedical Sciences Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 47 times in Thomson Reuters Web of Science Article | Citations
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Created: Sun, 01 Aug 2010, 10:08:05 EST