Vitamin-D status among patients with fractured neck of femur in Hong-Kong

Pun, K. K., Wong, F. H. W., Wang, C., Lau, P., Ho, P. W. M., Pun, W. K., Chow, S. P., Cheng, C. L., Leong, J. C. Y. and Young, R. T. T. (1990) Vitamin-D status among patients with fractured neck of femur in Hong-Kong. Bone, 11 5: 365-368. doi:10.1016/8756-3282(90)90092-D

Author Pun, K. K.
Wong, F. H. W.
Wang, C.
Lau, P.
Ho, P. W. M.
Pun, W. K.
Chow, S. P.
Cheng, C. L.
Leong, J. C. Y.
Young, R. T. T.
Title Vitamin-D status among patients with fractured neck of femur in Hong-Kong
Journal name Bone   Check publisher's open access policy
ISSN 8756-3282
Publication date 1990-01-01
Sub-type Article (original research)
DOI 10.1016/8756-3282(90)90092-D
Volume 11
Issue 5
Start page 365
End page 368
Total pages 4
Place of publication New York, USA
Publisher Elsevier Science
Language eng
Subject 110306 Endocrinology
Abstract Vitamin D deficiency leads to secondary hyperparathyroidism initially and then to mild osteomalacia, both of which conditions may be aymptomatic and may predispose to bone fracture. To assess the importance of vitamin D deficiency in predisposing to fractured neck of femur, we studied the vitamin D status, dietary intake and socio-economic characteristics in 69 patients with fractured neck of femur (group A), 28 normal subjects with age above 60 (group B), and 101 normal volunteers (group C). Patients with fractured neck of femor had significantly lower levels of serum 25-hydroxycholecalciferol compared with subjects of groups B and C. There is no statistically significant difference in other biochemical parameters, including calcium, phosphate, and alkaline phosphatase. Patients with fractured neck of femur and with 25-hydroxycholecalciferol below 20 ng/mL were characterized by a home-bound and/or institutionalized life-style, smaller living place, and limited access to open space. To conclude, hypovitaminosis D is a common problem among elderly patients with fractured neck of femur in Hong Kong. The fact that such vitamin D deficiency is associated with muscle weakness may contribute to falls, and thus indirectly account for an increased rate of hip fractures over the normal control.
Keyword Vitamin D deficiency
Hong Kong
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Institute for Molecular Bioscience - Publications
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Created: Tue, 20 Jul 2010, 00:51:58 EST by Laura McTaggart on behalf of Institute for Molecular Bioscience