Understanding and exploiting protein prenyltransferases

Nguyen, Uyen T. T., Goody, Roger S. and Alexandrov, Kirill (2010) Understanding and exploiting protein prenyltransferases. ChemBioChem, 11 9: 1194-1201. doi:10.1002/cbic.200900727

Attached Files (Some files may be inaccessible until you login with your UQ eSpace credentials)
Name Description MIMEType Size Downloads
HERDC_checklist.pdf HERDC checklist – not publicly available application/pdf 60.77KB 0

Author Nguyen, Uyen T. T.
Goody, Roger S.
Alexandrov, Kirill
Title Understanding and exploiting protein prenyltransferases
Journal name ChemBioChem   Check publisher's open access policy
ISSN 1439-4227
Publication date 2010-06-14
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1002/cbic.200900727
Open Access Status Not Open Access
Volume 11
Issue 9
Start page 1194
End page 1201
Total pages 8
Editor Peter Goelitz
Lisa J. Abel
Place of publication Weinheim, Germany
Publisher Wiley-VCH Verlag
Language eng
Formatted abstract
Lipidating proteins: Protein prenylation is catalyzed by protein prenyltransferases, and enables proteins to reversibly associate with intracellular membranes. The mechanisms of protein prenylation and the recent developments in analysis and biotechnological exploitation of these modifications are reviewed.
© 2010 Wiley-VCH Verlag GmbH & Co. KGaA.
Keyword Antitumor agents
Protein modifications
Protein prenylation
Geranylgeranyltransferase type-I
Farnesyl transferase inhibitors
Rab escort protein
Angstrom resolution
Diphosphate analogs
Posttranslational modification
Therapeutic intervention
Kinetic mechanism
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes 'Minireview'

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2011 Collection
Institute for Molecular Bioscience - Publications
Australian Institute for Bioengineering and Nanotechnology Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 30 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 31 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Sun, 18 Jul 2010, 10:08:06 EST