Point of care measurement of plasma creatinine in critically ill patients with acute kidney injury

Udy, A., O'Donoghue, S., D'Intini, V., Healy, H. and Lipman, J. (2009) Point of care measurement of plasma creatinine in critically ill patients with acute kidney injury. Anaesthesia, 64 4: 403-407. doi:10.1111/j.1365-2044.2008.05818.x


Author Udy, A.
O'Donoghue, S.
D'Intini, V.
Healy, H.
Lipman, J.
Title Point of care measurement of plasma creatinine in critically ill patients with acute kidney injury
Journal name Anaesthesia   Check publisher's open access policy
ISSN 0003-2409
Publication date 2009-03-13
Year available 2009
Sub-type Article (original research)
DOI 10.1111/j.1365-2044.2008.05818.x
Volume 64
Issue 4
Start page 403
End page 407
Total pages 5
Editor Dr D. Bogod
Place of publication United Kingdom
Publisher Wiley-Blackwell Publishing
Collection year 2010
Language eng
Subject C1
9201 Clinical Health (Organs, Diseases and Abnormal Conditions)
110312 Nephrology and Urology
Formatted abstract
We report the utility of an enzymatic point of care system for estimation of plasma creatinine concentration in critically ill patients with acute kidney injury. Multiple measurements were obtained from a heterogenous population admitted to a multi-disciplinary intensive care unit. The acute kidney injury network guidelines were used  to identify and stratify patients based on the creatinine concentration. Central laboratory values were used as comparators to assess the precision and bias of the system. Overall, point of care measurements correlated well with central pathology results (R2 = 0.991, p < 0.001), although there tended to be a small negative bias in
patients with acute kidney injury (3 lmol.l)1). The accuracy of point of care measurement is within clinically acceptable limits and given the much shorter turn around time can be used to identify and monitor patients with acute kidney injury in the critical care environment.
Keyword Acute Renal Failure
Plasma Creatine
Injury
Critically Ill Patients
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2010 Higher Education Research Data Collection
School of Medicine Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 14 times in Thomson Reuters Web of Science Article | Citations
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Created: Wed, 21 Apr 2010, 01:39:57 EST by Fiona Mactaggart on behalf of Anaesthesiology and Critical Care - RBWH