Human rhinoviruses: Coming in from the cold

Arden, Katherine E. and Mackay, Ian M. (2009) Human rhinoviruses: Coming in from the cold. Genome Medicine, 1 4: 44.1-44.5. doi:10.1186/gm44

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Author Arden, Katherine E.
Mackay, Ian M.
Title Human rhinoviruses: Coming in from the cold
Journal name Genome Medicine   Check publisher's open access policy
ISSN 1756-994X
Publication date 2009-04-01
Year available 2009
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1186/gm44
Open Access Status File (Publisher version)
Volume 1
Issue 4
Start page 44.1
End page 44.5
Total pages 5
Place of publication London, United Kingdom
Publisher Biomed Central
Language eng
Abstract Rhinovirus infections cause at least 70% of virus-related wheezing exacerbations and cold and flu-like illnesses. Infections are also associated with otitis media, sinusitis and pneumonia. The annual impact of human rhinovirus (HRV) infections costs billions of healthcare dollars. To date, 100 serotyped HRV or 'classical' strains have been divided between two genetically distinct species based on subgenomic sequences, but many more, apparently novel strains remain un-characterized, circulating in unknown patterns and causing undefined illnesses. Until recently, the genomes of less than half the classical strains had been sequenced. In April 2009, the remaining classical HRV genome sequences were reported. These data will inform therapeutic development and phylogenetic analysis for this subset of HRV strains but should be viewed as one step in a long road leading to comprehensive HRV characterization. Published: 28 April 2009 © 2009 BioMed Central Ltd
Keyword respiratory infection
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: 2010 Higher Education Research Data Collection
School of Chemistry and Molecular Biosciences
Clinical Medical Virology Centre Publications
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Citation counts: TR Web of Science Citation Count  Cited 11 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 11 times in Scopus Article | Citations
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Created: Wed, 10 Mar 2010, 22:12:14 EST by Lesley Arnicar on behalf of Clinical Medical Virology Centre