The efficacy of aloe vera used for burn wound healing: A systematic review

Maenthaisong, Ratree, Chaiyakunapruk, Nathorn, Niruntraporn, Surachet and Kongkaew, Chuenjid (2007) The efficacy of aloe vera used for burn wound healing: A systematic review. Burns, 33 6: 713-718. doi:10.1016/j.burns.2006.10.384

Author Maenthaisong, Ratree
Chaiyakunapruk, Nathorn
Niruntraporn, Surachet
Kongkaew, Chuenjid
Title The efficacy of aloe vera used for burn wound healing: A systematic review
Journal name Burns   Check publisher's open access policy
ISSN 0305-4179
Publication date 2007-09-01
Sub-type Article (original research)
DOI 10.1016/j.burns.2006.10.384
Open Access Status Not yet assessed
Volume 33
Issue 6
Start page 713
End page 718
Total pages 6
Place of publication Oxford, England
Publisher Elsevier Science
Language eng
Subject 1117 Public Health and Health Services
Abstract Aloe vera has been traditionally used for burn healing but clinical evidence remains unclear. We conducted a systematic review to determine the efficacy of topical aloe vera for the treatment of burn wounds. We electronically searched relevant studies in MEDLINE, CINAHL, Cochrane Library, HealthSTAR, DARE, South-East Asia Database, Chinese Databases, and several Thai local Databases (1918–June 2004). Only controlled clinical trials for burn healing were included. There were no restrictions on any language of publication. Two reviewers independently extracted data on study characteristics, patient characteristics, intervention, and outcome measure. Four studies with a total of 371 patients were included in this review. Based on a meta-analysis using duration of wound healing as an outcome measure, the summary weighted mean difference in healing time of the aloe vera group was 8.79 days shorter than those in the control group (P = 0.006). Due to the differences of products and outcome measures, there is paucity to draw a specific conclusion regarding the effect of aloe vera for burn wound healing. However, cumulative evidence tends to support that aloe vera might be an effective interventions used in burn wound healing for first to second degree burns. Further, well-designed trials with sufficient details of the contents of aloe vera products should be carried out to determine the effectiveness of aloe vera.
Keyword Aloe vera
Systematic review
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Public Health Publications
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Created: Wed, 06 Jan 2010, 18:37:31 EST by Ms Lynette Adams on behalf of School of Public Health