Patterns of linkage disequilibrium in multiple populations

Dreisigacker, S., Arief, V. N., DeLacy, I. H., Davenport, G., Manes, Y., Reynolds, M. P., Singh, R. P., Dieters, M. J. and Crossa, J. (2008). Patterns of linkage disequilibrium in multiple populations. In: R. Appels, R. Eastwood, E. Lagudah, P. Langridge, M. Mackay, L. McIntyre and P. Sharp, Proceedings of the 11th International Wheat Genetics Symposium. 11th International Wheat Genetics Symposium, Brisbane, Queensland, (). 24-29 August, 2008.

Author Dreisigacker, S.
Arief, V. N.
DeLacy, I. H.
Davenport, G.
Manes, Y.
Reynolds, M. P.
Singh, R. P.
Dieters, M. J.
Crossa, J.
Title of paper Patterns of linkage disequilibrium in multiple populations
Conference name 11th International Wheat Genetics Symposium
Conference location Brisbane, Queensland
Conference dates 24-29 August, 2008
Proceedings title Proceedings of the 11th International Wheat Genetics Symposium
Place of Publication Sydney, Australia
Publisher Sydney University Press
Publication Year 2008
Sub-type Fully published paper
Editor R. Appels
R. Eastwood
E. Lagudah
P. Langridge
M. Mackay
L. McIntyre
P. Sharp
Language eng
Formatted Abstract/Summary
Application of association analyses in plant breeding populations has the potential to revolutionize crop genetics. To determine the optimal strategies for implementing association analysis in wheat (Triticum aestivum L. subsp. aestivum) we analysed the structure of linkage disequilibrium (LD) across the genome in two distinct populations of CIMMYT wheat breeding germplasm. LD within a total of 645 advanced lines bred during the last 2 decades and distributed via CIMMYT Elite Spring Wheat Yield Trials and 160 synthetic hexaploid wheat (SHW) have been examined. Plant
materials were gentoyped with DArT markers plus additional microsatellite markers on a smaller set of lines to compare LD measures among marker technologies. Variable pattern of LD among chromosomes and the two marker technologies was
scored. Different patterns of LD decay were observed for advanced wheat lines and SHW. LD dropped faster in SHW and a lower percentage of loci pairs in LD was
detected demonstrating the usefulness of SHW for high resolution association analyses.
Subjects 0908 Food Sciences
Keyword Crop genetics
Triticum aestivum
Linkage disequilibrium
Q-Index Code EX
Q-Index Status Provisional Code

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Created: Wed, 16 Dec 2009, 15:12:53 EST by Thelma Whitbourne on behalf of Faculty Of Nat Resources, Agric & Veterinary Sc