The ipsilateral motor cortex contributes to cross-limb transfer of performance gains after ballistic motor practice

Lee, Michael, Hinder, Mark R., Gandevia, Simon C. and Carroll, Timothy J. (2009) The ipsilateral motor cortex contributes to cross-limb transfer of performance gains after ballistic motor practice. The Journal of Physiology, 588 1: 201-212. doi:10.1113/jphysiol.2009.183855

Author Lee, Michael
Hinder, Mark R.
Gandevia, Simon C.
Carroll, Timothy J.
Title The ipsilateral motor cortex contributes to cross-limb transfer of performance gains after ballistic motor practice
Journal name The Journal of Physiology   Check publisher's open access policy
ISSN 0022-3751
Publication date 2009-11-16
Year available 2010
Sub-type Article (original research)
DOI 10.1113/jphysiol.2009.183855
Open Access Status DOI
Volume 588
Issue 1
Start page 201
End page 212
Total pages 12
Editor William A. Large
Place of publication Bethesda, MD
Publisher American Physiological Society
Language eng
Subject C1
970117 Expanding Knowledge in Psychology and Cognitive Sciences
110603 Motor Control
1109 Neurosciences
Abstract Although it has long been known that practicing a motor task with one limb can improve performance with the limb opposite, the mechanisms remain poorly understood. Here we tested the hypothesis that improved performance with the untrained limb on a fastest possible (i.e. ballistic) movement task depends partly on cortical circuits located ipsilateral to the trained limb. The idea that crossed effects, which are important for the learning process, might occur in the ‘untrained' hemisphere following ballistic training is based on the observation that tasks requiring strong descending drive generate extensive bilateral cortical activity. Twenty-one volunteers practiced a ballistic index finger abduction task with their right hand, and corticospinal excitability was assessed in two hand muscles (first dorsal interosseus, FDI; adductor digiti minimi, ADM). Eight control subjects did not train. After training, repetitive transcranial magnetic stimulation (rTMS; 15 min at 1 Hz) was applied to the left (trained) or right (untrained) motor cortex to induce a ‘virtual lesion'. A third training group received sham rTMS, and control subjects received rTMS to the right motor cortex. Performance and corticospinal excitability (for FDI) increased in both hands for training but not control subjects. rTMS of the left, trained motor cortex specifically reduced training-induced gains in motor performance for the right, trained hand, and rTMS of the right, untrained motor cortex specifically reduced performance gains for the left, untrained hand. Thus, cortical processes within the untrained hemisphere, ipsilateral to the trained hand, contribute to early retention of ballistic performance gains for the untrained limb.
Keyword transcranial magnetic stimulation
low-frequency RTMS
intermanual transfer
Finger Movements
corticospinal excitability
different complexities
Cortical Excitability
voluntary contraction
possible mechanisms
bilateral transfer
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Online first 16/11/2009

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2010 Higher Education Research Data Collection
School of Human Movement and Nutrition Sciences Publications
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Created: Wed, 25 Nov 2009, 22:47:47 EST by Deborah Noon on behalf of School of Human Movement and Nutrition Sciences