Effect of osteoporosis on morphology and mobility of the lumbar spine

Yang, Zhengyi, Griffith, James F., Leung, Ping Chung and Lee, Raymond (2009) Effect of osteoporosis on morphology and mobility of the lumbar spine. Spine, 34 3: E115-E121. doi:10.1097/BRS.0b013e3181895aca

Author Yang, Zhengyi
Griffith, James F.
Leung, Ping Chung
Lee, Raymond
Title Effect of osteoporosis on morphology and mobility of the lumbar spine
Journal name Spine   Check publisher's open access policy
ISSN 0362-2436
Publication date 2009-02-01
Year available 2009
Sub-type Article (original research)
DOI 10.1097/BRS.0b013e3181895aca
Open Access Status Not yet assessed
Volume 34
Issue 3
Start page E115
End page E121
Total pages 7
Editor James N. Weinstein
Place of publication Philadelphia, PA, United States
Publisher Lippincott Williams & Wilkins
Language eng
Subject C1
110601 Biomechanics
920499 Public Health (excl. Specific Population Health) not elsewhere classified
Formatted abstract
Study Design. Cross-sectional study.
Objective. The purpose of this study was to examine disc morphology and spinal mobility in subjects with varying degrees of osteoporosis.
Summary of Background Data. There was limited information on the effect of osteoporosis on lumbar morphology and spinal mobility. It was also unclear how osteoporosis affects the nonosseous tissues such as the intervertebral disc.
Methods. Ninety elderly subjects with varying bone mineral densities (22 normal, 28 osteopenia, 40 osteoporosis) were recruited from an osteoporosis clinic. Lateral radiographs and magnetic resonance images of their lumbar spines were obtained. An electromagnetic tracking device was employed to measure the ranges of motion of the whole lumbar spine.
Results. Although the thoracic spine had been shown to have decreased anterior vertebral body height in subjects with osteoporosis, this study revealed that the anterior height was increased in the lumbar region. Osteoporosis was associated with expansion of the middle of the disc with corresponding collapse of vertebral bodies, but osteoporosis was found not to be related to either disc preservation or degeneration. No significant change in spinal mobility was observed in patients with osteoporosis.
Conclusion. Osteoporosis does not only affect the bone but also the nonosseous tissues. It was found to be associated with expansion of the intervertebral disc, which was likely to be secondary to changes in the vertebral endplate.
Keyword Intervertebral disc
Lumbar spine
Spinal mobility
Q-Index Code C1
Q-Index Status Confirmed Code
Grant ID CERG CUHK5251/04E
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2010 Higher Education Research Data Collection
ERA 2012 Admin Only
Centre for Advanced Imaging Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 13 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 16 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Thu, 03 Sep 2009, 18:43:26 EST by Mr Andrew Martlew on behalf of Centre For Magnetic Resonance