The cost effectiveness of naltrexone added to cognitive-behavioral therapy in the treatment of alcohol dependence

Walters, David, Connor, Jason P., Feeney, Gerald F. X. and Young, Ross McD (2009) The cost effectiveness of naltrexone added to cognitive-behavioral therapy in the treatment of alcohol dependence. Journal of Addictive Diseases, 28 2: 137-144. doi:10.1080/10550880902772456


Author Walters, David
Connor, Jason P.
Feeney, Gerald F. X.
Young, Ross McD
Title The cost effectiveness of naltrexone added to cognitive-behavioral therapy in the treatment of alcohol dependence
Journal name Journal of Addictive Diseases   Check publisher's open access policy
ISSN 1055-0887
1545-0848
Publication date 2009-01-01
Year available 2009
Sub-type Article (original research)
DOI 10.1080/10550880902772456
Open Access Status Not yet assessed
Volume 28
Issue 2
Start page 137
End page 144
Total pages 8
Editor B. Stimmel
S. Singh
Place of publication United States
Publisher Routledge
Language eng
Subject C1
920209 Mental Health Services
110321 Rehabilitation and Therapy (excl. Physiotherapy)
Abstract The purpose of this study was to evaluate the comparative cost of treating alcohol dependence with either cognitive behavioral therapy (CBT) alone or CBT combined with naltrexone (CBT+naltrexone). Two hundred ninety-eight outpatients dependent on alcohol who were consecutively treated for alcohol dependence participated in this study. One hundred seven (36%) patients received adjunctive pharmacotherapy (CBT+naltrexone). The Drug Abuse Treatment Cost Analysis Program was used to estimate treatment costs. Adjunctive pharmacotherapy (CBT+naltrexone) introduced an additional treatment cost and was 54% more expensive than CBT alone. When treatment abstinence rates (36.1% CBT; 62.6% CBT+naltrexone) were applied to cost effectiveness ratios, CBT+naltrexone demonstrated an advantage over CBT alone. There were no differences between groups on a preference-based health measure (SF-6D). In this treatment center, to achieve 100 abstainers over a 12-week program, 280 patients require CBT compared with 160 CBT+naltrexone. The dominant choice was CBT+naltrexone based on modest economic advantages and significant efficiencies in the numbers needed to treat.
Keyword cost-effectiveness
CBT
alcohol treatment
naltrexone
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

 
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Created: Thu, 03 Sep 2009, 18:21:34 EST by Mr Andrew Martlew on behalf of Psychiatry - Royal Brisbane and Women's Hospital