Dietary protein during gestation affects circulating indicators of placental function and fetal development in heifers

Sullivan, T. M., Micke, G. C., Soares Magalhaes, R., Martin, G. B., Wallace, C. R., Green, J. A. and Perry, V. E. A. (2009) Dietary protein during gestation affects circulating indicators of placental function and fetal development in heifers. Placenta, 30 4: 348-354. doi:10.1016/j.placenta.2009.01.008


Author Sullivan, T. M.
Micke, G. C.
Soares Magalhaes, R.
Martin, G. B.
Wallace, C. R.
Green, J. A.
Perry, V. E. A.
Title Dietary protein during gestation affects circulating indicators of placental function and fetal development in heifers
Journal name Placenta   Check publisher's open access policy
ISSN 0143-4004
Publication date 2009-04-01
Year available 2009
Sub-type Article (original research)
DOI 10.1016/j.placenta.2009.01.008
Open Access Status Not yet assessed
Volume 30
Issue 4
Start page 348
End page 354
Total pages 7
Editor Michael Nelson
Place of publication United Kingdom
Publisher Elsevier
Language eng
Subject 0702 Animal Production
07 Agricultural and Veterinary Sciences
C1
Abstract The influences of nutritional protein during the first and second trimesters of pregnancy on placental hormones and fetal growth were determined in composite beef heifers. At artificial insemination, heifers were stratified by weight within each composite genotype into 4 treatment groups: High High (HH ¼ 1.4 kg crude protein (CP)/day for first and second trimesters of gestation; n ¼ 16), High Low (HL ¼ 1.4 kg CP/day for first trimester and 0.4 kg CP/day for second trimester; n ¼ 19), Low High (LH ¼ 0.4 kg CP/day for first trimester and 1.4 kg CP/day for second trimester; n ¼ 17) or Low Low (LL ¼ 0.4 kg CP/day for first and second trimesters; n ¼ 19). Maternal plasma bovine pregnancy associated glycoprotein (bPAG) and progesterone (P4) were determined at gestation day (gd) 28, 82, 179 and 271 (mean gestation length 286 days) in addition to P4 at term. Estrone sulphate (ES) and bovine placental lactogen (bPL) concentrations were measured at gd 124, 179, 236 and 271 and at term in addition to ES at gd 82. Low dietary protein increased placental function as indicated by increased bPAG (P< 0.001) and ES (P¼ 0.02) concentrations in first trimester and increased bPL concentrations (P ¼ 0.01) in the second trimester of gestation. In the third trimester, when dietary treatment had ceased, placental function was no longer associated with previous dietary treatments. Dam genotype affected placental function as measured by bPL (P< 0.001) and ES concentrations (P¼ 0.02). Calf gender, heifer age and maternal insulin-like growth factor (IGF)-I, -II and leptin did not affect hormonal indicators or circulating markers of placental function. Enhanced placental function during the third trimester, as measured by ES, was associated with increased calf birth weight (P¼ 0.003).
Keyword Cattle
Growth factor I
Bovine pregnancy associated glycoprotein
Bovine placental lactogen
Estrone sulphate
Placenta
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2010 Higher Education Research Data Collection
School of Public Health Publications
School of Veterinary Science Publications
 
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Created: Thu, 03 Sep 2009, 18:20:04 EST by Mr Andrew Martlew on behalf of Faculty Of Nat Resources, Agric & Veterinary Sc