Strain rate evaluation of phasic atrial function in hypertension

Eshoo, S., Boyd, A. C., Ross, D. L., Marwick, T. H. and Thomas, L (2009) Strain rate evaluation of phasic atrial function in hypertension. Heart, 95 14: 1184-1191. doi:10.1136/hrt.2008.156208

Author Eshoo, S.
Boyd, A. C.
Ross, D. L.
Marwick, T. H.
Thomas, L
Title Strain rate evaluation of phasic atrial function in hypertension
Journal name Heart   Check publisher's open access policy
ISSN 1355-6037
Publication date 2009-07-15
Sub-type Article (original research)
DOI 10.1136/hrt.2008.156208
Open Access Status DOI
Volume 95
Issue 14
Start page 1184
End page 1191
Total pages 8
Place of publication London, U.K.
Publisher BMJ Group
Language eng
Formatted abstract
Background: Strain (SI) and strain rate (SR) measure regional myocardial deformation and may be a new technique to assess phasic atrial function.

Objective: To examine the feasibility of using SI and SR to evaluate phasic atrial function in patients with mild hypertension (HT).

Patients and methods: The study group comprised 54 patients with mild essential HT (29 women) and 80 age-matched normal controls (47 women). Standard two-dimensional and Doppler echocardiography was performed as well as Doppler tissue imaging. The following left atrial (LA) volumes were measured: (a) maximal LA volume or Volmax; (b) minimal LA volume or Volmin; (c) just before the “p” wave on ECG (Volp). Phasic LA volumes were also calculated. Systolic (S-Sr), early diastolic (E-Sr), late diastolic (A-Sr) strain rate and SI were measured.

Results: Despite no differences in indexed maximal LA volume with only mild increases in left ventricular mass in the HT cohort compared with normal subjects (mean (SD) 86 (18) g/m2 vs 67 (14) g/m2; pā€Š=ā€Š0.001), E-Sr was significantly lower in the HT cohort. There was a corresponding reduction in indexed conduit volume in the HT cohort compared with normal subjects (10.5 (7.5) ml/m2 vs 13.8 (6.1) ml/m2; pā€Š=ā€Š0.006). Global E-Sr showed modest negative correlations with LA Volmax and LA ejection fraction. No significant difference was present in S-Sr, A-Sr or global atrial strain between the normal and HT cohorts.

Conclusion: Mild HT results in a reduction in LA conduit volume, although maximal LA volume is unchanged. This is reflected by a reduction in E-Sr with preserved S-Sr and A-Sr.
Keyword Mechanical function
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 39 times in Thomson Reuters Web of Science Article | Citations
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Created: Thu, 03 Sep 2009, 17:56:07 EST by Mr Andrew Martlew on behalf of Medicine - Princess Alexandra Hospital