Bone growth is enhanced by novel bioceramic coatings on Ti alloy implants

Wang, Chaoyuan, Karlis, Gross A., Anderson, Gail I., Dunstan, Colin R., Carbone, Angelo, Berger, Goerg, Ploska, Ute and Zreiqat, Hala (2009) Bone growth is enhanced by novel bioceramic coatings on Ti alloy implants. Journal of Biomedical Materials Research - Part A, 90A 2: 419-428. doi:10.1002/jbm.a.32111

Author Wang, Chaoyuan
Karlis, Gross A.
Anderson, Gail I.
Dunstan, Colin R.
Carbone, Angelo
Berger, Goerg
Ploska, Ute
Zreiqat, Hala
Title Bone growth is enhanced by novel bioceramic coatings on Ti alloy implants
Journal name Journal of Biomedical Materials Research - Part A   Check publisher's open access policy
ISSN 1549-3296
Publication date 2009-08-01
Year available 2008
Sub-type Article (original research)
DOI 10.1002/jbm.a.32111
Open Access Status DOI
Volume 90A
Issue 2
Start page 419
End page 428
Total pages 10
Place of publication Hoboken, NJ, United States
Publisher John Wiley & Sons
Language eng
Formatted abstract
Calcium phosphate ceramics are widely used as coating materials to orthopedic implants and are found to enhance initial bony ingrowth by stimulating osseous apposition to the implant surface. In this study, two novel calcium orthophosphate materials were selected for coating onto the commonly used orthopedic implant material Ti-6Al- 4V. One was calcium alkali orthophosphate with the crystalline phase Ca10[K/Na](PO4)7 with a small addition of SiO2 (AW-Si) and the other was calcium orthophosphate composed of 70 mol % fluorapatite, Ca10(PO4)6F2 and 30 mol % CaZr4(PO4)6 (FA7Z). The coated implants were placed in cortical and cortico-cancellous bone of sheep femur for six weeks. Retrieved samples were tested for osseointegration and mechanical strength. It was found that both coatings produced enhanced bone/implant contact rate compared to the control when implanted in cortico-cancellous bone. This study demonstrates that the two coatings have the capability of encouraging bone growth, and hence the potential for being used as coating materials on Ti implants.
Keyword Orthopedic implants
Ceramic coatings
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ
Additional Notes Article first published online: 3 JUN 2008

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Veterinary Science Publications
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Citation counts: TR Web of Science Citation Count  Cited 18 times in Thomson Reuters Web of Science Article | Citations
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Created: Thu, 03 Sep 2009, 17:50:33 EST by Mr Andrew Martlew on behalf of School of Veterinary Science