A meta-analytic assessment of the Thyroglobulin marker for marbling in beef cattle

Wood, Ian A., Moser, Gerhard, Burrell, Daniel L., Mengersen, Kerrie L. and Hetzel, D. Jay S. (2006) A meta-analytic assessment of the Thyroglobulin marker for marbling in beef cattle. Genetics Selection Evolution, 38 5: 479-494. doi:10.1051/gse:2006016


Author Wood, Ian A.
Moser, Gerhard
Burrell, Daniel L.
Mengersen, Kerrie L.
Hetzel, D. Jay S.
Title A meta-analytic assessment of the Thyroglobulin marker for marbling in beef cattle
Journal name Genetics Selection Evolution   Check publisher's open access policy
ISSN 0999-193X
1297-9686
Publication date 2006-01-01
Year available 2006
Sub-type Article (original research)
DOI 10.1051/gse:2006016
Open Access Status DOI
Volume 38
Issue 5
Start page 479
End page 494
Total pages 16
Place of publication London, United Kingdom
Publisher BioMed Central
Language eng
Abstract A meta-analysis was undertaken reporting on the association between a polymorphism in the Thyroglobulin gene (TG5) and marbling in beef cattle. A Bayesian hierarchical model was adopted, with alternative representations assessed through sensitivity analysis. Based on the overall posterior means and posterior probabilities, there is substantial support for an additive association between the TG5 marker and marbling. The marker effect was also assessed across various breed groups, with each group displaying a high probability of positive association between the T allele and marbling. The WinBUGS program code used to simulate the model is included as an Appendix available online at www.edpsciences.org/gse.
Keyword Bayesian hierarchical model
Meta-analysis
Association studies
TG5 marker
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Mathematics and Physics
 
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Created: Tue, 19 May 2009, 01:08:56 EST by Ms Lynette Adams on behalf of School of Mathematics & Physics