Cyclotides: Natural, Circular Plant Peptides that possess significant activity against Gastrointestinal nematode parasites of sheep

Colgrave, M. L., Kotze, A. C., Huang, Y., O'Grady, J., Simonsen, S. M. and Craik, D. J. (2008) Cyclotides: Natural, Circular Plant Peptides that possess significant activity against Gastrointestinal nematode parasites of sheep. Biochemistry, 47 20: 5581-5589. doi:10.1021/bi800223y


Author Colgrave, M. L.
Kotze, A. C.
Huang, Y.
O'Grady, J.
Simonsen, S. M.
Craik, D. J.
Title Cyclotides: Natural, Circular Plant Peptides that possess significant activity against Gastrointestinal nematode parasites of sheep
Journal name Biochemistry   Check publisher's open access policy
ISSN 0006-2960
Publication date 2008-04-22
Year available 2008
Sub-type Article (original research)
DOI 10.1021/bi800223y
Open Access Status Not yet assessed
Volume 47
Issue 20
Start page 5581
End page 5589
Total pages 8
Place of publication Easton
Publisher American Chemical Society
Language eng
Subject C1
030401 Biologically Active Molecules
860701 Animal Protection Chemicals
Abstract The cyclotides are a novel family of backbone-cyclized cystine-knot containing peptides from plants that have been shown to possess insecticidal activity against Helicoverpa larvae, an important pest of corn and cotton. In the current study, we investigated the in vitro effects of the cycloides on the viability of egg, larval, and adult life stages of two species of economically important gastrointestinal nermatode parasites of livestock, Hermonchus contortus and Trichostrongylus colubriformis.
Keyword Biochemistry & Molecular Biology
Biochemistry & Molecular Biology
BIOCHEMISTRY & MOLECULAR BIOLOGY
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: 2009 Higher Education Research Data Collection
 
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Created: Thu, 16 Apr 2009, 20:30:56 EST by Cody Mudgway on behalf of Institute for Molecular Bioscience