Cyclotides as natural anti-HIV agents

Ireland, David C., Wang, Conan K., Wilson, Jennifer A., Gustafson, Kirk R. and Craik, David J. (2008) Cyclotides as natural anti-HIV agents. Biopolymers: Peptide Science, 90 1: 51-60. doi:10.1002/bip.20886


Author Ireland, David C.
Wang, Conan K.
Wilson, Jennifer A.
Gustafson, Kirk R.
Craik, David J.
Title Cyclotides as natural anti-HIV agents
Journal name Biopolymers: Peptide Science   Check publisher's open access policy
ISSN 0006-3525
Publication date 2008-01-01
Year available 2008
Sub-type Article (original research)
DOI 10.1002/bip.20886
Open Access Status Not yet assessed
Volume 90
Issue 1
Start page 51
End page 60
Total pages 9
Place of publication New York
Publisher John Wiley & Sons
Language eng
Subject 030401 Biologically Active Molecules
C1
860899 Human Pharmaceutical Products not elsewhere classified
Abstract Cyclotides are disulfide rich macrocyclic plant peptides that are defined by their unique topology in which a head-to-tail cyclized backbone is knotted by the interlocking arrangement of three disulfide bonds. This cyclic cystine knot motif gives the cyclotides exceptional resistance to thermal, chemical, or enzymatic degradation.
Keyword circular proteins
cyclic cystine knot
HIV
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ
Additional Notes Published Online: Nov 15 2007 12:09PM, in Print January 2008

Document type: Journal Article
Sub-type: Article (original research)
Collection: Institute for Molecular Bioscience - Publications
 
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Created: Thu, 16 Apr 2009, 20:13:53 EST by Cody Mudgway on behalf of Institute for Molecular Bioscience