Hopping Hotspots: Global Shifts in Marine Biodiversity

Renema, W., Bellwood, D.R., Braga, J.C., Bromfield, K., Hall, R., Johnson, K.G., Lunt, P., Meyer, C.P., McMonagle, L.B., Morley, R.J., O'Dea, A., Todd, J.A., Wesselingh, F.P., Wilson, M.E.J. and Pandolfi, J.M. (2008) Hopping Hotspots: Global Shifts in Marine Biodiversity. Science, 321 5889: 654-657. doi:10.1126/science.1155674


Author Renema, W.
Bellwood, D.R.
Braga, J.C.
Bromfield, K.
Hall, R.
Johnson, K.G.
Lunt, P.
Meyer, C.P.
McMonagle, L.B.
Morley, R.J.
O'Dea, A.
Todd, J.A.
Wesselingh, F.P.
Wilson, M.E.J.
Pandolfi, J.M.
Title Hopping Hotspots: Global Shifts in Marine Biodiversity
Journal name Science   Check publisher's open access policy
ISSN 0036-8075
Publication date 2008-08-01
Year available 2008
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1126/science.1155674
Open Access Status Not Open Access
Volume 321
Issue 5889
Start page 654
End page 657
Total pages 4
Editor Kennedy, D.
Bradford, M.
Place of publication United States
Publisher American Association for the Advancement of Science
Language eng
Subject C1
960808 Marine Flora, Fauna and Biodiversity
060205 Marine and Estuarine Ecology (incl. Marine Ichthyology)
060303 Biological Adaptation
Abstract The Global Programme to Eliminate Lymphatic Filariasis (LF) aims to eliminate the disease as a public health problem by 2020 by conducting mass drug administration (MDA) and controlling morbidity. Once elimination targets have been reached, surveillance is critical for ensuring that programmatic gains are sustained, and challenges include timely identification of residual areas of transmission. WHO guidelines encourage cost-efficient surveillance, such as integration with other population-based surveys. In American Samoa, where LF is caused by Wuchereria bancrofti, and Aedes polynesiensis is the main vector, the LF elimination program has made significant progress. Seven rounds of MDA (albendazole and diethycarbamazine) were completed from 2000 to 2006, and Transmission Assessment Surveys were passed in 2010/2011 and 2015. However, a seroprevalence study using an adult serum bank collected in 2010 detected two potential residual foci of transmission, with Og4C3 antigen (Ag) prevalence of 30.8% and 15.6%. We conducted a follow up study in 2014 to verify if transmission was truly occurring by comparing seroprevalence between residents of suspected hotspots and residents of other villages. In adults from non-hotspot villages (N = 602), seroprevalence of Ag (ICT or Og4C3), Bm14 antibody (Ab) and Wb123 Ab were 1.2% (95% CI 0.6-2.6%), 9.6% (95% CI 7.5%-12.3%), and 10.5% (95% CI 7.6-14.3%), respectively. Comparatively, adult residents of Fagali'i (N = 38) had significantly higher seroprevalence of Ag (26.9%, 95% CI 17.3-39.4%), Bm14 Ab (43.4%, 95% CI 32.4-55.0%), and Wb123 Ab 55.2% (95% CI 39.6-69.8%). Adult residents of Ili'ili/Vaitogi/Futiga (N = 113) also had higher prevalence of Ag and Ab, but differences were not statistically significant. The presence of transmission was demonstrated by 1.1% Ag prevalence (95% CI 0.2% to 3.1%) in 283 children aged 7-13 years who lived in one of the suspected hotspots; and microfilaraemia in four individuals, all of whom lived in the suspected hotspots, including a 9 year old child. Our results provide field evidence that integrating LF surveillance with other surveys is effective and feasible for identifying potential hotspots, and conducting surveillance at worksites provides an efficient method of sampling large populations of adults.
Keyword Multidisciplinary Sciences
Science & Technology - Other Topics
MULTIDISCIPLINARY SCIENCES
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: 2009 Higher Education Research Data Collection
School of Earth Sciences Publications
Ecology Centre Publications
Centre for Marine Studies Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 184 times in Thomson Reuters Web of Science Article | Citations
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Created: Thu, 16 Apr 2009, 03:36:01 EST by Peter Fogarty on behalf of Centre for Marine Studies