Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptide

Dutertre, Sébastien, Croker, Daniel, Daly, Norelle L., Andersson, Åsa, Muttenthaler, Markus, Lumsden, Natalie G., Craik, David J., Alewood, Paul F., Guillon, Gilles and Lewis, Richard J. (2008) Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptide. Journal of Biological Chemistry, 283 11: 7100-7108. doi:10.1074/jbc.M706477200

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Author Dutertre, Sébastien
Croker, Daniel
Daly, Norelle L.
Andersson, Åsa
Muttenthaler, Markus
Lumsden, Natalie G.
Craik, David J.
Alewood, Paul F.
Guillon, Gilles
Lewis, Richard J.
Title Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptide
Formatted title
Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like Peptide 
Journal name Journal of Biological Chemistry   Check publisher's open access policy
ISSN 0021-9258
Publication date 2008-03-14
Year available 2008
Sub-type Article (original research)
DOI 10.1074/jbc.M706477200
Open Access Status File (Publisher version)
Volume 283
Issue 11
Start page 7100
End page 7108
Total pages 8
Place of publication Baltimore, MD, U. S. A.
Publisher American Society for Biochemistry & Molecular Biology
Language eng
Subject C1
030401 Biologically Active Molecules
970107 Expanding Knowledge in the Agricultural and Veterinary Sciences
Abstract We report the discovery of conopressing-T, a novel bioactive peptide isolated from Conus tulipa venom. Conopressin-T belongs to the vasopressin-like peptide family and displays high sequence homology to the mammalian hormone oxytocin (OT) and to vasotocin, the endogenerous vasopressin analogue found in the teleost fish, the cone snail's prey.
Keyword Biochemistry & Molecular Biology
Biochemistry & Molecular Biology
BIOCHEMISTRY & MOLECULAR BIOLOGY
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes First Published on January 2, 2008

 
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Created: Thu, 16 Apr 2009, 00:59:29 EST by Cody Mudgway on behalf of Institute for Molecular Bioscience