SOCS3 as a tumor suppressor in breast cancer cells, and its regulation by PRL

Barclay, Johanna L., Anderson, Stephen T., Waters, Michael J. and Curlewis, Jon D. (2009) SOCS3 as a tumor suppressor in breast cancer cells, and its regulation by PRL. International Journal of Cancer, 124 8: 1756-1766. doi:10.1002/ijc.24172


Author Barclay, Johanna L.
Anderson, Stephen T.
Waters, Michael J.
Curlewis, Jon D.
Title SOCS3 as a tumor suppressor in breast cancer cells, and its regulation by PRL
Journal name International Journal of Cancer   Check publisher's open access policy
ISSN 0020-7136
1097-0215
Publication date 2009-04-01
Year available 2008
Sub-type Article (original research)
DOI 10.1002/ijc.24172
Open Access Status
Volume 124
Issue 8
Start page 1756
End page 1766
Total pages 11
Editor H. zur Hausen
Place of publication New York
Publisher Wiley-Liss
Language eng
Subject C1
060405 Gene Expression (incl. Microarray and other genome-wide approaches)
920106 Endocrine Organs and Diseases (excl. Diabetes)
Abstract Suppressor of cytokine signaling 3 (SOCS3), as a key regulator of cytokine signaling, has the potential to modulate numerous cellular processes. Its involvement in inflammatory disease is well established, and there is an increasing evidence for a role in breast cancer as a regulator of signal transducers and activators of transcription (STATS).
Keyword SOCS3
breast cancer
prolactin
STAT
Sp1
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

 
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Created: Tue, 14 Apr 2009, 20:35:30 EST by Cody Mudgway on behalf of Institute for Molecular Bioscience