Acute neuropathic pain: diagnosis and treatment

Gray, Paul D. (2008) Acute neuropathic pain: diagnosis and treatment. Current Opinion in Anaesthesiology, 21 5: 590-595. doi:10.1097/ACO.0b013e32830c900c

Author Gray, Paul D.
Title Acute neuropathic pain: diagnosis and treatment
Journal name Current Opinion in Anaesthesiology   Check publisher's open access policy
ISSN 0952-7907
Publication date 2008-10-01
Year available 2008
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1097/ACO.0b013e32830c900c
Volume 21
Issue 5
Start page 590
End page 595
Total pages 6
Editor Hugo van Aken
Paul G. Barash
Place of publication New York, United States
Publisher Lippincott Williams & Wilkins
Language eng
Subject 920111 Nervous System and Disorders
110906 Sensory Systems
Formatted abstract
Purpose of review: Acute neuropathic pain (ANP) is a condition that is under-recognized, often difficult to treat and one that may progress to persistent pain and disability. This review examines the diagnosis and treatment in order to assist clinicians in providing better care to patients with this debilitating pain.

Recent findings:
The recent development of psychometric scales for the detection of neuropathic pain may assist in diagnosing ANP, though this is yet to be tested. Specific research into the treatment of ANP is sparse. However, several recent trials have shown that both tramadol and gabapentin are useful in mitigating neuropathic cancer pain. In addition, a recent trial suggests a combination of neural blockade with memantine may be useful in reducing ANP.

The diagnosis of ANP is assisted by knowledge of the medical circumstances that have a higher risk of the condition developing, a detailed pain history with a directed examination and use of neuropathic pain scales. Although the data are lacking, agents that have demonstrated efficacy in persistent neuropathic pain states should be used in ANP. Refractory ANP could be treated with either intravenous lidocaine or calcitonin. Future research should be directed at validating a scale of neuropathic pain in ANP and conducting more therapeutic trials.
Keyword Acute neuropathic pain
Pain management
Q-Index Code C1
Q-Index Status Provisional Code

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 18 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 26 times in Scopus Article | Citations
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Created: Sat, 11 Apr 2009, 00:25:37 EST by Sia Athanasas on behalf of Anaesthesiology and Critical Care - RBWH