Immediate and late outcomes of transarterial coil occlusion of patent ductus arteriosus in dogs

Campbell, F. E., Thomas, W. P., Miller, S. J., Berger, D. and Kittleson, M. D. (2006) Immediate and late outcomes of transarterial coil occlusion of patent ductus arteriosus in dogs. Journal of Veterinary Internal Medicine, 20 1: 83-96. doi:10.1892/0891-6640(2006)20[83:IALOOT]2.0.CO;2


Author Campbell, F. E.
Thomas, W. P.
Miller, S. J.
Berger, D.
Kittleson, M. D.
Title Immediate and late outcomes of transarterial coil occlusion of patent ductus arteriosus in dogs
Journal name Journal of Veterinary Internal Medicine   Check publisher's open access policy
ISSN 0891-6640
1939-1676
Publication date 2006-01-01
Sub-type Article (original research)
DOI 10.1892/0891-6640(2006)20[83:IALOOT]2.0.CO;2
Open Access Status DOI
Volume 20
Issue 1
Start page 83
End page 96
Total pages 14
Place of publication Hoboken, NJ, United States
Publisher Wiley-Blackwell Publishing
Language eng
Subject 0707 Veterinary Sciences
Formatted abstract
Records from dogs (n = 125) that underwent attempted transarterial coil occlusion of patent ductus arteriosus (PDA) at the University of California, Davis, between 1998 and 2003, were reviewed, and a subset of these dogs (n = 31) in which the procedure was performed at least 12 months earlier were reexamined to determine long-term outcome. Coil implantation was achieved in 108 dogs (86%). Despite immediate complete ductal closure in only 34% of dogs, the procedure was hemodynamically successful as evidenced by a reduction in indexed left ventricular internal diameter in diastole (LVIDd; P < .0001), fractional shortening (P < .0001), and left atrial to aortic ratio (LA: Ao; P = .022) within 24 hours. Complete ductal closure was documented in 61% of dogs examined 12 to 63 months after coil occlusion. Long-standing residual ductal flow in the other 39% of dogs was not associated with increased indexed LVIDd or LA: Ao and was not hemodynamically relevant. Repeat intervention was deemed advisable in only 4 dogs with persistent (n = 1) or recurrent (n = 3) ductal flow. Complications included aberrant embolization (n = 27), death (n = 3), ductal reopening (n = 3), transient hemoglobinuria (n = 2), hemorrhage (n = 1), aberrant coil placement (n = 1), pulmonary hypertension (n = 1), and skin abscessation (n = 1). Serious infectious complications did not occur despite antibiotic administration to only 40% of these dogs. Transarterial coil occlusion was not possible in 14 dogs (11%) because of coil instability in the PDA and was associated with increased indexed minimum ductal diameter (P = .03), LVIDd (P = .0002), LVIDs (P = 0.001), and congestive left heart failure (P = .03) reflecting a relatively large shunt volume.
Keyword Canine
Coil embolization
Congenital heart disease
Echocardiography
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes Previously presented as an abstract at the ECVIM annual meeting in Barcelona, Spain, in September 2004.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Veterinary Science Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 34 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 43 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Thu, 09 Apr 2009, 21:54:42 EST by Ms Lynette Adams on behalf of School of Veterinary Science