Chronic Disease Modeling

Habbema, J., Boer, R. and Barendregt, J. (2008). Chronic Disease Modeling. In Kristian Heggenhougen and Stella Quah (Ed.), International Encyclopedia of Public Health (pp. 704-709) San Diego, CA, U.S.A.: Academic Press. doi:10.1016/B978-012373960-5.00329-4

Author Habbema, J.
Boer, R.
Barendregt, J.
Title of chapter Chronic Disease Modeling
Title of book International Encyclopedia of Public Health
Place of Publication San Diego, CA, U.S.A.
Publisher Academic Press
Publication Year 2008
Sub-type Chapter in reference work, encyclopaedia, manual or handbook
DOI 10.1016/B978-012373960-5.00329-4
Open Access Status
Year available 2008
ISBN 9780122272257
Editor Kristian Heggenhougen
Stella Quah
Volume number 1
Start page 704
End page 709
Total pages 6
Total chapters 30
Language eng
Subjects 1117 Public Health and Health Services
Abstract/Summary Modeling of chronic diseases should answer research questions on these diseases and their health impact. Models can assess the impact on population health of prevention, early detection, diagnostics and treatment, in terms of reduction in mortality, incidence, and quality of life. Models can include age, sex, time, risk factors, disease states, population dynamics, and heterogeneities, dependencies, and stochasticities. For simple models, analytical and numerical solutions are possible. In macrosimulation, the unit of simulation is a group. In microsimulation, a life history is simulated for each individual. This allows for more complex modeling, at the cost of increased complexity in controlling the model. The population context of the models can be single cohort, multiple cohort, and a full dynamic population. Effort is needed for producing models with formal validity, face validity, data validity, internal validity, and external validity. A number of published models are discussed.
Keyword Chronic disease
Cohort model
Dynamic population model
Health effects
Markov model
Multistate model
Risk factors
Q-Index Code BX
Q-Index Status Provisional Code
Institutional Status UQ

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Created: Thu, 09 Apr 2009, 20:38:47 EST by Geraldine Fitzgerald on behalf of School of Public Health