Recombinant Hepatitis B surface antigen vaccines for the delivery of disease-related antigens.

Tindle, Robert W., Oscar Haigh, Gould, Allan R. and Scott Thomson (2008) Recombinant Hepatitis B surface antigen vaccines for the delivery of disease-related antigens.. Current Trends in Immunology, 9 51-60.

Author Tindle, Robert W.
Oscar Haigh
Gould, Allan R.
Scott Thomson
Title Recombinant Hepatitis B surface antigen vaccines for the delivery of disease-related antigens.
Journal name Current Trends in Immunology   Check publisher's open access policy
ISSN 0972-4567
Publication date 2008-01-01
Year available 2008
Sub-type Critical review of research, literature review, critical commentary
Open Access Status Not Open Access
Volume 9
Start page 51
End page 60
Total pages 10
Editor Research Trends
Place of publication India
Publisher Research Trends Pty Ltd
Language eng
Subject C1
060502 Infectious Agents
060506 Virology
920109 Infectious Diseases
Abstract The extraordinary immunogenicity of the envelope protein of Hepatitis B virus (HBsAg) has been exploited to derive the pan-global vaccine to prevent Hepatitis B virus infection. HBsAg protein molecules spontaneously associate within the bipid layer to form empty virus-like particles (VLPs). Here we discuss ways in which HBsAg can be genetically engineered to derive recombinant DNA or VLP vaccines for pathogen associated diseases and some tumors which depend upon the adaptive immune response for prevention or resolution.
Keyword hepatitis B surface antigen
vaccine vector
Dna
virus-like particle
Cytotoxic T Cell
antibody
Q-Index Code C1
Q-Index Status Confirmed Code
Additional Notes This journal has not yet been listed on Ulrich's but is part of the stable Current Trends in Virology. Statement received from editor confirming peer review.

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: 2009 Higher Education Research Data Collection
Clinical Medical Virology Centre Publications
 
Versions
Version Filter Type
Citation counts: Scopus Citation Count Cited 0 times in Scopus Article
Google Scholar Search Google Scholar
Created: Thu, 09 Apr 2009, 00:58:12 EST by Lesley Arnicar on behalf of Clinical Medical Virology Centre