Instrument-, Age- and Site-Dependent Variations of Dermoscopic Patterns of Congenital Melanocytic Naevi: A Multicentre Study

Seidenari, S., Pellacani, G., Martella, A., Giusti, F., Argenziano, G., Buccini, P., Carli, P., Catricalà, C., De Giorgi, V., Ferrari, A., Ingordo, V., Manganoni, A. M., Peris, K., Piccolo, D. and Pizzichetta, M. A. (2006) Instrument-, Age- and Site-Dependent Variations of Dermoscopic Patterns of Congenital Melanocytic Naevi: A Multicentre Study. British Journal of Dermatology, 155 1: 56-61. doi:10.1111/j.1365-2133.2006.07182.x


Author Seidenari, S.
Pellacani, G.
Martella, A.
Giusti, F.
Argenziano, G.
Buccini, P.
Carli, P.
Catricalà, C.
De Giorgi, V.
Ferrari, A.
Ingordo, V.
Manganoni, A. M.
Peris, K.
Piccolo, D.
Pizzichetta, M. A.
Title Instrument-, Age- and Site-Dependent Variations of Dermoscopic Patterns of Congenital Melanocytic Naevi: A Multicentre Study
Journal name British Journal of Dermatology   Check publisher's open access policy
ISSN 1365-2133
0007-0963
Publication date 2006-07-01
Year available 2006
Sub-type Article (original research)
DOI 10.1111/j.1365-2133.2006.07182.x
Open Access Status Not yet assessed
Volume 155
Issue 1
Start page 56
End page 61
Total pages 6
Editor John English
Place of publication London
Publisher Blackwell
Language eng
Subject 110304 Dermatology
Formatted abstract
Background: Recently, we identified and described dermoscopic aspects, present with a higher frequency in congenital melanocytic lesions with respect to acquired naevi. We also classified small- and medium-sized congenital naevi (CN) into nine subtypes according to their macroscopic and dermoscopic aspects.

Objectives: Because the recognition of dermoscopic features may be instrument dependent, in this study, we wanted to check whether dermoscopic patterns specific for CN can be identified in digital images acquired by means of different instruments. We also wanted to check the validity of our previously proposed classification and assess possible age- and site-dependent variations of dermoscopic patterns and naevus subtypes.

Patients/methods: Images corresponding to 384 small- or medium-sized CN were collected in eight different centres employing four different instruments. Lesion images were evaluated and checked for the presence of specific dermoscopic criteria, classified, and compared with a database of 350 acquired naevi.

Results: Specific and unspecific dermoscopic features were identifiable in images acquired by means of all four instrument types. The mean number of identified features per lesion did not vary according to the instrument employed for the acquisition of the images; however, it was lower for lesions recorded employing low magnifications. The previously proposed classification was easily applied to the whole image database. The variegated naevus type was identified as a highly specific clinical/dermoscopic pattern. Dermoscopic features varied according to age and location. The globular type prevailed in subjects under 11 years of age and on the trunk, whereas the majority of reticular lesions were located on the limbs.

Conclusions: Because definite clinical and histological criteria for the diagnosis of the congenital nature of naevi are lacking, the use of dermoscopy can be of great help in identifying those lesions where the presence of specific dermoscopic features makes the diagnosis of CN more likely. Moreover, dermoscopy can be useful both for the classification of lesions already identified as congenital according to definite clinical and anamnestic data and for a possible correlation of naevus phenotype and dermoscopic patterns to the risk of developing a malignant melanoma in prospective studies.
Keyword congenital naevi
dermoscopy
melanocytic naevi
videomicroscopy
Q-Index Code C1
Additional Notes Published Online: 2 March 2006

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 37 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 48 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Fri, 03 Apr 2009, 20:30:42 EST by Mary-Anne Marrington on behalf of School of Medicine