Biotransformation of mefenamic acid by cell suspension cultures of Solanum mammosum

Surodjo, S., Salim, A. ., Suciati, Syahrani, A., Indrayanto, G. and Garson, M.J. (2008) Biotransformation of mefenamic acid by cell suspension cultures of Solanum mammosum. Natural Product Communications, 3 2: 257-262.

Author Surodjo, S.
Salim, A. .
Suciati
Syahrani, A.
Indrayanto, G.
Garson, M.J.
Title Biotransformation of mefenamic acid by cell suspension cultures of Solanum mammosum
Formatted title
Biotransormation of mefenamic acid by cell suspension cultures of Solanum mammosum
Journal name Natural Product Communications   Check publisher's open access policy
ISSN 1934-578X
1555-9475
Publication date 2008-01-01
Year available 2008
Sub-type Article (original research)
Open Access Status Not yet assessed
Volume 3
Issue 2
Start page 257
End page 262
Total pages 6
Place of publication Westerville, OH, United States
Publisher Natural Product
Language eng
Subject C1
030599 Organic Chemistry not elsewhere classified
970103 Expanding Knowledge in the Chemical Sciences
Abstract Five biotransformation products, mefenamic acid-7-O-beta-D-glucopyranosyl ester (2), mefenamic acid-7-O-beta-D-(beta-1,6-O-D-glucopyranosyl)-glucopyranosyl ester (3), mefenamic acid-7-O-beta-D-(beta-1,2-O-D-glucopyranosyl)-glucopyranosyl ester (4), mefenamic acid-7-O-beta-D-(beta-1,6-O-D-glucopyranosyl)-2-glucopyranose ester (5), and mefenamic acid-7-O-alpha-D-(beta-1,6-O-D-glucopyranosyl)-2-glucopyranose ester (6) were isolated from cell suspension cultures of Solanum mammosum following administration of the therapeutic agent mefenamic acid (1). The structures of all new compounds were elucidated on the basis of their NMR and mass spectrometric data.
Keyword Mefenamic acid
biotransformation
glycosylation
Solanum mammosum
cell suspension cultures
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2009 Higher Education Research Data Collection
School of Chemistry and Molecular Biosciences
 
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Created: Fri, 03 Apr 2009, 19:02:40 EST by Jennifer Falknau on behalf of School of Chemistry & Molecular Biosciences