Meta-analyses of the incidence and prevalence of schizophrenia: conceptual and methodological issues

Saha, Sukanta, Chant, David C. and McGrath, John J. (2008) Meta-analyses of the incidence and prevalence of schizophrenia: conceptual and methodological issues. International Journal of Methods in Psychiatric Research, 17 1: 55-61. doi:10.1002/mpr.240


Author Saha, Sukanta
Chant, David C.
McGrath, John J.
Title Meta-analyses of the incidence and prevalence of schizophrenia: conceptual and methodological issues
Journal name International Journal of Methods in Psychiatric Research   Check publisher's open access policy
ISSN 1049-8931
Publication date 2008-02-19
Year available 2008
Sub-type Article (original research)
DOI 10.1002/mpr.240
Open Access Status Not yet assessed
Volume 17
Issue 1
Start page 55
End page 61
Total pages 7
Place of publication United Kingdom
Publisher John Wiley & Sons Ltd.
Language eng
Subject C1
321204 Mental Health
730211 Mental health
Abstract While meta-analytic techniques are routine in the synthesis of data from randomized controlled trials, there are no clear guidelines on how best to summarize frequency data such as incidence and prevalence estimates. Based on data from two recent systematic reviews of the incidence and prevalence of schizophrenia, this paper explores some of the conceptual and methodological issues related to the meta-analyses of frequency estimates in epidemiology. Because variations in the incidence and prevalence of disorders such as schizophrenia can be informative, there is a case against collapsing data into one pooled estimate. Variations in frequency estimates can be displayed graphically, or summarized with quantiles around measures of central tendency. If pooled estimated are of interest, then researchers need to be aware that studies based on large samples will leverage greater weight on the pooled value. Based on systematic reviews of the incidence and prevalence Of schizophrenia, we explore if these and related issues are of practical concern. When used with appropriate caution, meta-analysis can complement the synthesis of frequency data in epidemiology; however, researchers interested in variation should not rely on meta-analysis alone. Copyright (C) 2008 John Wiley & Sons, Ltd.
Keyword Psychiatry
Psychiatry
PSYCHIATRY, SCI
PSYCHIATRY, SSCI
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2009 Higher Education Research Data Collection
Queensland Brain Institute Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 55 times in Thomson Reuters Web of Science Article | Citations
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Created: Fri, 03 Apr 2009, 02:40:25 EST by Debra McMurtrie on behalf of Queensland Brain Institute