Low positive predictive value of a nucleic acid amplification test for nongenital Neisseria gonorrhoeae infection in homosexual men

McNally, Leon P., Templeton, David J., Jin, Fengyi, Grulich, Andrew E., Donovan, Basil, Whiley, David M. and Cunningham, Philip H. (2008) Low positive predictive value of a nucleic acid amplification test for nongenital Neisseria gonorrhoeae infection in homosexual men. Clinical Infectious Diseases, 47 2: e25-e27. doi:10.1086/589299


Author McNally, Leon P.
Templeton, David J.
Jin, Fengyi
Grulich, Andrew E.
Donovan, Basil
Whiley, David M.
Cunningham, Philip H.
Title Low positive predictive value of a nucleic acid amplification test for nongenital Neisseria gonorrhoeae infection in homosexual men
Formatted title
Low positive predictive value of a nucleic acid amplification test for nongenital Neisseria gonorrhoeae infection in homosexual men
Journal name Clinical Infectious Diseases   Check publisher's open access policy
ISSN 1058-4838
1537-6591
Publication date 2008-07-01
Sub-type Article (original research)
DOI 10.1086/589299
Open Access Status
Volume 47
Issue 2
Start page e25
End page e27
Total pages 3
Editor S. L. Gorbach
Place of publication Cary, NC, United States
Publisher Oxford University Press
Language eng
Subject C1
060502 Infectious Agents
060506 Virology
060503 Microbial Genetics
920109 Infectious Diseases
920501 Child Health
Formatted abstract
The diagnosis of nongenital Neisseria gonorrhoeae infection by the Becton Dickinson Probe Tec ET Chlamydia trachomatis and N. gonorrhoeae Amplified DNA assay had low positive predictive value among an Australian community-based sample of homosexual men. Only 30.5% of oropharyngeal samples and 73.7% of anorectal samples were positive for N.gonorrhoeae by the porA assay. The accuracy of nucleic acid amplification tests in this context is compromised without supplemental testing.
Keyword Neisseria gonorrhoeae
nongenital infection
Amplified DNA assay
Homosexual Men
oropharyngeal samples
anorectal samples
porA assay
nucleic acid amplification tests
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2009 Higher Education Research Data Collection
Clinical Medical Virology Centre Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 24 times in Thomson Reuters Web of Science Article | Citations
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Created: Thu, 02 Apr 2009, 20:29:36 EST by Lesley Arnicar on behalf of Clinical Medical Virology Centre