Dermoscopic Changes in Acral Melanocytic Nevi During Digital Follow-up

Altamura, Davide, Zalaudek, Iris, Sera, Francesco, Argenziano, Giuseppe, Fargnoli, Maria Concetta, Rossiello, Luigi and Peris, Ketty (2007) Dermoscopic Changes in Acral Melanocytic Nevi During Digital Follow-up. Archives of Dermatology, 143 11: 1372-1376. doi:10.1001/archderm.143.11.1372

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Author Altamura, Davide
Zalaudek, Iris
Sera, Francesco
Argenziano, Giuseppe
Fargnoli, Maria Concetta
Rossiello, Luigi
Peris, Ketty
Title Dermoscopic Changes in Acral Melanocytic Nevi During Digital Follow-up
Journal name Archives of Dermatology   Check publisher's open access policy
ISSN 0003-987X
Publication date 2007-11-01
Sub-type Article (original research)
DOI 10.1001/archderm.143.11.1372
Open Access Status File (Publisher version)
Volume 143
Issue 11
Start page 1372
End page 1376
Total pages 5
Place of publication Chicago, Ill.
Publisher American Medical Association
Language eng
Subject 110304 Dermatology
Formatted abstract
Objective To investigate changes in dermoscopic patterns of acquired acral melanocytic nevi (AAMN) over time.

Design Retrospective analysis of digital dermoscopic follow-up of 230 AAMN located on acral volar skin.

Setting Outpatient clinics at university dermatology departments.
Patients A total of 230 AAMN located on the soles (n = 149), fingers (n = 62), and palms (n = 19), of 230 white subjects 14 years or younger (n = 81), 15 to 30 years (n = 72), and older than 30 years (n = 77).

Main Outcome Measure Comparison of baseline and follow-up dermoscopic patterns.

Results Individual AAMN had a digital follow-up of 6 months (n = 59), 12 months (n = 74), 18 months (n = 44), and 24 months (n = 53). Baseline dermoscopic images showed the following patterns: parallel furrow (48.8%), latticelike (16.1%), fibrillar (10.9%), nontypical (10.9%), homogeneous (4.8%), globular (3.5%), transition (3.5%), and reticular (2.6%). Dermoscopic changes over time were observed in 42 of the 230 AAMN (18.3%), with the greatest frequency of changes occurring in patients 14 years or younger (23 of 81 lesions; 28.4%) (P = .005). The parallel furrow pattern (25.9%) showed more variations over time than other dermoscopic patterns (11.0%) (P = .004). The frequency of change increased linearly over time (P = .001). Four of 7 clinically regressing nevi showed a homogeneous pattern at the last examination.

Conclusions Dermoscopic changes of AAMN are most common in subjects younger than 14 years. The parallel furrow pattern appears to be the dermoscopic pattern most subject to change, while the homogeneous pattern may be seen also in AAMN showing clinical and dermoscopic involution.

Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
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