Organic anions and potassium salts in nutrition and metabolism

Demigné, Christian, Sabboh, Houda, Puel, Caroline, Rémésy, Christian and Coxam, Véronique (2004) Organic anions and potassium salts in nutrition and metabolism. Nutrition research reviews, 17 2: 249-258. doi:10.1079/NRR200485


Author Demigné, Christian
Sabboh, Houda
Puel, Caroline
Rémésy, Christian
Coxam, Véronique
Title Organic anions and potassium salts in nutrition and metabolism
Journal name Nutrition research reviews   Check publisher's open access policy
ISSN 1475-2700
0954-4224
Publication date 2004-12-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1079/NRR200485
Open Access Status
Volume 17
Issue 2
Start page 249
End page 258
Total pages 10
Place of publication Cambridge
Publisher Cambridge University Press for the Nutrition Soceity
Language eng
Subject 111199 Nutrition and Dietetics not elsewhere classified
Abstract The present review examines the importance of dietary organic anions in preventive nutrition. Organic anions are chiefly supplied by plant foods, as partially neutralised K salts such as potassium citrate, potassium malate and, to a lesser extent, oxalate or tartrate salts. Animal products may also supply K anions, essentially as phosphate, but also as lactate as a result of fermentative or maturation processes, but these K salts have little alkalinising significance. Citrate and malate anions are absorbed in the upper digestive tract, while a substantial proportion is probably metabolised in the splanchnic area. Whatever their site of metabolism, these anions finally yield KHCO3 which is used by the kidneys to neutralise fixed acidity. This acidity essentially reflects the oxidation of excess S amino acids to sulfate ions, which is mainly related to the dietary protein level. Failure to neutralise acidity leads to low-grade metabolic acidosis, with possible long-term deleterious effects on bone Ca status and on protein status. Furthermore, low-grade acidosis is liable to affect other metabolic processes, such as peroxidation of biological structures. These metabolic disturbances could be connected with the relatively high incidence of osteoporosis and muscle-protein wasting problems observed in ageing individuals in Europe and Northern America. Providing a sufficient supply of K organic anions through fruit and vegetable intake should be recommended, fostering the actual motivational campaigns ('five (or ten) per d') already launched to promote the intake of plant foods rich in complex carbohydrates and various micronutrients.
Keyword Organic anions
Potassium
Calcium
Metabolic acidosis
Osteoporosis
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Excellence in Research Australia (ERA) - Collection
Centre for Nutrition and Food Sciences Publications
 
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Created: Thu, 02 Apr 2009, 00:43:38 EST by Ms Lynette Adams on behalf of Centre for Nutrition and Food Sciences