Two-stage aqueous two-phase extractions: selection of system composition using a genetic algorithm

Bleier, J., Syddall, M., Lyddiatt, A. and Chen, X. D. (2004) Two-stage aqueous two-phase extractions: selection of system composition using a genetic algorithm. Biochemical Engineering Journal, 21 3: 199-205. doi:10.1016/j.bej.2004.05.011


Author Bleier, J.
Syddall, M.
Lyddiatt, A.
Chen, X. D.
Title Two-stage aqueous two-phase extractions: selection of system composition using a genetic algorithm
Journal name Biochemical Engineering Journal   Check publisher's open access policy
ISSN 1369-703X
Publication date 2004-11-01
Sub-type Article (original research)
DOI 10.1016/j.bej.2004.05.011
Open Access Status Not Open Access
Volume 21
Issue 3
Start page 199
End page 205
Total pages 7
Place of publication New York
Publisher Elsevier
Language eng
Subject 090404 Membrane and Separation Technologies
Abstract A genetic algorithm (GA) was applied to search for optimal protein recovery from two two-stage aqueous two-phase (A2P) extractions. The first contained only BSA and the second contained citrated whole bovine blood. This work shows that GAs can be applied to the problem of obtaining an effective combination of forward and back extractions for the recovery of proteins from a biological material. The GA performed the task in a short time and required little prior knowledge of the behaviour of the system.
Keyword aqueous two-phase systems
back extraction
genetic algorithm
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
Centre for Military and Veterans' Health Publications
 
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Created: Wed, 01 Apr 2009, 18:49:47 EST by Ms Julie Schofield on behalf of Centre for Australian Military & Veterans' Health