Solitary extramedullary plasmacytoma of the canine larynx

Hayes, A. M., Gregory, S. P., Murphy, S., McConnell, J. F. and Patterson-Kane, J. C. (2007) Solitary extramedullary plasmacytoma of the canine larynx. Journal of Small Animal Practice, 48 5: 288-291. doi:10.1111/j.1748-5827.2006.00265.x

Author Hayes, A. M.
Gregory, S. P.
Murphy, S.
McConnell, J. F.
Patterson-Kane, J. C.
Title Solitary extramedullary plasmacytoma of the canine larynx
Journal name Journal of Small Animal Practice   Check publisher's open access policy
ISSN 0022-4510
Publication date 2007-05-01
Sub-type Article (original research)
DOI 10.1111/j.1748-5827.2006.00265.x
Open Access Status
Volume 48
Issue 5
Start page 288
End page 291
Total pages 4
Place of publication Oxford, United Kingdom
Publisher Wiley-Blackwell Publishing
Language eng
Subject 070709 Veterinary Pathology
Abstract An 11-year-old, female, spayed cocker spaniel was presented with dysphonia caused by a solitary laryngeal mass. Excisional biopsy was performed, and a diagnosis of plasmacytoma was made on the basis of histological examination. Further investigations showed no signs of systemic involvement. Coarse fractionated radiation therapy failed to control the tumour. Therapy was successfully instituted with a conventional combination chemotherapy protocol over a period of 14 months. The dog remains disease free 30 months after diagnosis. Most solitary, extramedullary plasmacytomas in dogs arise in the gastrointestinal tract, with fewer reports in other sites. The larynx is an uncommon sight of involvement in any species, and to the authors' knowledge, this is the first report of this tumour type in the canine larynx. In contrast to the therapeutic benefits reported in humans, the combination of surgery and radiation therapy was unsuccessful in this case, although sustained remission was gained following chemotherapy.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes "Case report"

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
ERA 2012 Admin Only
School of Veterinary Science Publications
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Created: Tue, 31 Mar 2009, 23:51:49 EST by Ms Lynette Adams on behalf of School of Veterinary Science