Changing epidemiology of methicillin-resistant S. aureus in Queensland, Australia, 2000-2006: use of passive surveillance of susceptibility phenotypes

Nimmo, Graeme R., Fong, J., Paterson, David and McLaws, M. L. (2008) Changing epidemiology of methicillin-resistant S. aureus in Queensland, Australia, 2000-2006: use of passive surveillance of susceptibility phenotypes. Journal of Hospital Infection, 70 4: 305-313. doi:10.1016/j.jhin.2008.07.003


Author Nimmo, Graeme R.
Fong, J.
Paterson, David
McLaws, M. L.
Title Changing epidemiology of methicillin-resistant S. aureus in Queensland, Australia, 2000-2006: use of passive surveillance of susceptibility phenotypes
Journal name Journal of Hospital Infection   Check publisher's open access policy
ISSN 0195-6701
Publication date 2008-12-01
Year available 2008
Sub-type Article (original research)
DOI 10.1016/j.jhin.2008.07.003
Open Access Status Not yet assessed
Volume 70
Issue 4
Start page 305
End page 313
Total pages 9
Editor S. Barrett
Place of publication London, U.K.
Publisher W.B. Saunders
Language eng
Subject 920109 Infectious Diseases
110309 Infectious Diseases
Abstract The epidemiology of meticillin-resistant S. aureus (MRSA) infection has changed remarkably in recent years with the appearance of new MRSA strains causing infections in the community. These strains have now begun to cause healthcare-associated infections. The ability to track such changes is necessary to guide clinical and public health action. Here we report passive surveillance of all public laboratory susceptibility data in Queensland to track changes in MRSA phenotypes corresponding to the major epidemic strains from 2000 to 2006. The inpatient rate of MRSA isolation from pus, tissue and fluid (PTF) and blood culture (BC) specimens declined by 26% and 35%, respectively. The rate of isolation of the AUS-2/3-like phenotype (corresponding to ST239-MRSA-III) decreased from 651 to 242 isolates per million accrued patient days in inpatient PTF and BC, whereas that for non-multi resistant MRSA (nmMRSA, corresponding to community MRSA strains) increased from 71 to 315. The overall outpatient rate of MRSA isolation from PTF and BC increased by 224% and 31%, respectively. The rate of AUS-2/3-like isolates in outpatient PTF decreased from 131 to 60 per million outpatient occasions of service while the nmMRSA rate increased from 52 to 490. Surveillance of phenotypes derived from routine susceptibility data is a useful tool. for tracking changes in the epidemiology of MRSA over large geographical regions. Crown Copyright (c) 2008 Published by Elsevier Ltd on behalf of The Hospital Infection Society. All rights reserved.
Keyword Infectious Diseases
Infectious Diseases
INFECTIOUS DISEASES
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: UQ Centre for Clinical Research Publications
 
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Created: Sun, 29 Mar 2009, 21:41:31 EST by Carmen Buttery on behalf of UQ Centre for Clinical Research