Therapeutic vaccination against cervical cancer – are we near?

Merja Ruutu, Frazer, Ian H. and Liu, Xiaosong (2008) Therapeutic vaccination against cervical cancer – are we near?. Cancer Forum, 32 2: 98-105.


Author Merja Ruutu
Frazer, Ian H.
Liu, Xiaosong
Title Therapeutic vaccination against cervical cancer – are we near?
Journal name Cancer Forum   Check publisher's open access policy
ISSN 0311-306X
Publication date 2008-07-01
Year available 2008
Sub-type Article (original research)
Volume 32
Issue 2
Start page 98
End page 105
Total pages 7
Place of publication Australia
Publisher Cancer Council Australia
Language eng
Subject C1
920102 Cancer and Related Disorders
110709 Tumour Immunology
Abstract Therapeutic vaccines developed to target the papillomavirus antigens that are expressed by cervical cancer induce immune responses, but have yet to show clinical efficacy. Transplantable tumour models expressing human papillomavirus antigens do not predict vaccine outcome in the clinic. Understanding how immune responses are influenced in a tumour antigen experienced host, and what surrogate marker or markers reflect the potential efficacy of therapeutic vaccines in the clinic, will be necessary to provide new approaches to immunotherapy for cervical cancer.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2009 Higher Education Research Data Collection
UQ Diamantina Institute Publications
 
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Created: Thu, 26 Mar 2009, 01:18:04 EST by Kylie Hengst on behalf of UQ Diamantina Institute