Early childhood adversity and adolescent depression: the mediating role of continued stress

Hazel, N. A., Hammen, C., Brennan, P. A. and Najman, J. M. (2008) Early childhood adversity and adolescent depression: the mediating role of continued stress. Psychological Medicine, 38 4: 581-589. doi:10.1017/S0033291708002857

Attached Files (Some files may be inaccessible until you login with your UQ eSpace credentials)
Name Description MIMEType Size Downloads
Early__childhood.pdf Author copy application/pdf 251.67KB 0

Author Hazel, N. A.
Hammen, C.
Brennan, P. A.
Najman, J. M.
Title Early childhood adversity and adolescent depression: the mediating role of continued stress
Journal name Psychological Medicine   Check publisher's open access policy
ISSN 0033-2917
1469-8978
Publication date 2008-01-01
Year available 2008
Sub-type Article (original research)
DOI 10.1017/S0033291708002857
Open Access Status File (Author Post-print)
Volume 38
Issue 4
Start page 581
End page 589
Total pages 9
Editor Eugene Paykel
Kenneth Kendler
Place of publication Cambridge, UK
Publisher Cambridge University Press
Language eng
Subject C1
111714 Mental Health
920413 Social Structure and Health
Abstract Background. While various conceptualizations of the link between childhood adversity and later depression have been offered, most have not accounted for the possibility that early adversity predicts continuing stress proximal to depression onset. Thus, the present study tested the possible mediating role of recent stress in the association between early adversity and depression in late adolescence.
Formatted abstract
Background
While various conceptualizations of the link between childhood adversity and later depression have been offered, most have not accounted for the possibility that early adversity predicts continuing stress proximal to depression onset. Thus, the present study tested the possible mediating role of recent stress in the association between early adversity and depression in late adolescence.

Method
Study questions were examined in a longitudinal community sample of 705 youth who were contemporaneously assessed for early adversity exposure prior to age 5 years, chronic and episodic stress at age 15 years, and major depression prior to age 15 years and between 15 and 20 years.

Results
Total youth stress burden at age 15 years mediated the effect of early adversity on depression between ages 15 and 20 years, and none of the observed relationships were moderated by onset of depression prior to age 15 years.

Conclusions
These findings suggest that continued stress exposure proximal to depression onset largely accounts for the association between early adversity and depression in late adolescence. Intervention should thus focus on disrupting the continuity of stressful conditions across childhood and adolescence. Future studies of the neurobiological and psychosocial mechanisms of the link between early experiences and depression should explore whether the effects of early experiences are independent of continuing adversity proximal to depressive onset.
Keyword depression
early adversity
stress
Q-Index Code C1
Q-Index Status Confirmed Code
Grant ID R01 MH52239
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2009 Higher Education Research Data Collection
School of Public Health Publications
School of Social Science Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 74 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 75 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Wed, 25 Mar 2009, 22:15:26 EST by Margaret Gately on behalf of School of Social Science