Use of Hormone Replacement Therapy (HRT) among Women Aged 45–64 Years in the German EPIC-cohorts

Nagel, Gabriele, Lahmann, Petra H, Schulz, Mandy, Boeing, Heiner and Linseisen, Jakob (2007) Use of Hormone Replacement Therapy (HRT) among Women Aged 45–64 Years in the German EPIC-cohorts. Maturitas, 56 4: 436-446. doi:10.1016/j.maturitas.2006.11.008

Author Nagel, Gabriele
Lahmann, Petra H
Schulz, Mandy
Boeing, Heiner
Linseisen, Jakob
Title Use of Hormone Replacement Therapy (HRT) among Women Aged 45–64 Years in the German EPIC-cohorts
Journal name Maturitas   Check publisher's open access policy
ISSN 0378-5122
Publication date 2007-04-20
Sub-type Article (original research)
DOI 10.1016/j.maturitas.2006.11.008
Open Access Status DOI
Volume 56
Issue 4
Start page 436
End page 446
Total pages 11
Place of publication Clare, Ireland
Publisher Elsevier Scientific Publishers
Language eng
Subject 1117 Public Health and Health Services
Abstract Objective: To describe the prevalence and to assess type and indicators of hormone replacement therapy (HRT) use in the two German EPIC-cohorts. Methods: Approximately 30,000 women predominantly aged 35–65 years were recruited in EPIC-Heidelberg and EPICPotsdam between 1994 and 1998. Information on diet and lifestyle, medical history and use of hormone therapy was collected at recruitment. Prevalence and type of HRT-regime was described and logistic regression models used to examine correlates of HRT-use. Results: Among women aged 45–64 years, 37.9% in Heidelberg and 35.8% in Potsdam were current HRT users. Among current users without bilateral oophorectomy, 40.5% in Heidelberg and 23.7% in Potsdam used HRT for at least 5 years. Most women in Heidelberg were taking cyclic combined or estrogen monotherapy, whereas in Potsdam both continuous combined and cyclic combined therapies were most frequently used. In both centres, older age, ever use of oral contraceptives, and alcohol consumption were indicators for both current and ever HRT-use. HRT-use was less frequent in obese women as compared to women with lower BMI. In Potsdam, but not in Heidelberg, higher education and current smoking were associated with HRT-use. Conclusion: In both German EPIC-cohorts, the prevalence of medication withHRTis high compared to other European countries. Types of exogenous hormones used differed by centre. Various reproductive and lifestyle characteristics were identified as correlates of HRT-use. © 2006 Elsevier Ireland Ltd. All rights reserved.
Keyword Hormone replacement therapy (HRT)
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
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