Unique Family Clustering of Human Echinococcosis cases in a Chinese Community

Yang, Yu Rong, Ellis, Magda, Sun, Tao, Li, Zhengzhi, Liu, Xongzhou, Vuitton, Dominique A,, Bartholomot, Brigitte, Giraudoix, Patrick, Craig, Philip S., Boufana, Belchis, Wang,, Yungaui, Feng, Xiaohui, Wen, Hao, Ito, Akira and McManus, Donald P. (2006) Unique Family Clustering of Human Echinococcosis cases in a Chinese Community. American Journal of Tropical Medicine and Hygiene, 74 3: 487-494.

Author Yang, Yu Rong
Ellis, Magda
Sun, Tao
Li, Zhengzhi
Liu, Xongzhou
Vuitton, Dominique A,
Bartholomot, Brigitte
Giraudoix, Patrick
Craig, Philip S.
Boufana, Belchis
Wang,, Yungaui
Feng, Xiaohui
Wen, Hao
Ito, Akira
McManus, Donald P.
Title Unique Family Clustering of Human Echinococcosis cases in a Chinese Community
Journal name American Journal of Tropical Medicine and Hygiene   Check publisher's open access policy
ISSN 0002-9637
Publication date 2006-01-01
Sub-type Article (original research)
Open Access Status Not yet assessed
Volume 74
Issue 3
Start page 487
End page 494
Total pages 8
Place of publication Northbrook, IL
Publisher American Society for Tropical Medicine and Hygiene
Language eng
Subject 1117 Public Health and Health Services
Abstract We have identified a significant focus and unusual clustering of human cases of cystic echinococcosis (CE) and alveolar echinococcosis (AE) in the village of Nanwan, Xiji County, Ningxia Hui Autonomous Region, in one of the most highly endemic areas for both diseases in China. The village, a Chinese Hui Islamic community, is composed of 167 members of four extended families. A total of 28 people died (12 of echinococcosis) since the village was first settled in the 1950s. Despite similar life patterns, the number of AE and CE cases occurring in each family was different. Overall, the prevalences of AE and CE were 9% (20 cases) and 5.9% (13 cases), with a combined prevalence of 14.9%. In contrast to CE, a comparison of the prevalence of AE indicated significant differences between the four family clusters. Although suggestive that host genotype might play a role in susceptibility to AE, this hypothesis requires further investigation.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Public Health Publications
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Created: Tue, 24 Mar 2009, 21:48:06 EST by Maryanne Watson on behalf of School of Public Health